Protein Alignment Gad1 and DPL1

DIOPT Version :10

• Sequence 1: NP_523914.2
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_010580.1
• Gene: DPL1 / 851888
• SGDID: S000002702
• Length: 589
• Species: Saccharomyces cerevisiae
• Alignment Length: 555
• Identity: 100/555 - (18%)
• Similarity: 185/555 - (33%)
• Gaps: 164/555 - (29%)

  Fly    44 LLD--FVKATNDR-----NEKVLDFHHPEDMKRLLDLDVPDRALPLQQLIEDCATTLKYQVKTGH 101
            |||  |::.|.::     .:.:.|.....|.:.:....:|...:|...:||:
Yeast   100 LLDSPFLRGTVEKEVTKVKQSIEDELIRSDSQLMNFPQLPSNGIPQDDVIEE------------- 151

  Fly   102 PHFFNQLSN-------------------GLDLISMAGEWLTATANTNMFTYEIAPVFILMENVVL 147
               .|:|::                   |.|||.:...........|....::.|....||:.|:
Yeast   152 ---LNKLNDLIPHTQWKEGKVSGAVYHGGDDLIHLQTIAYEKYCVANQLHPDVFPAVRKMESEVV 213

  Fly   148 TKMREIIGWSG--GDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPGTLVMFTSDQCHYSI 210
            :.:..:.....  |......||:.|.|.|.|:|  ||:..:  |..:..|..:...|:   |...
Yeast   214 SMVLRMFNAPSDTGCGTTTSGGTESLLLACLSA--KMYALH--HRGITEPEIIAPVTA---HAGF 271

  Fly   211 KSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVL--------- 266
            ...|...|:...|..:.|:       |.:::        .|.:..|:|.   .|:|
Yeast   272 DKAAYYFGMKLRHVELDPT-------TYQVD--------LGKVKKFINK---NTILLVGSAPNFP 318

  Fly   267 -GAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRK-----------HRHPRFTGVERADSVTWN 319
             |..|||..:..|.|||...:|:|:..|..::...:           .|.|..|      |::.:
Yeast   319 HGIADDIEGLGKIAQKYKLPLHVDSCLGSFIVSFMEKAGYKNLPLLDFRVPGVT------SISCD 377

  Fly   320 PHKLMGALLQCSTIHFKEDGLLISCNQMSAEYL--FMTDKQYDISYDTGDK----VIQCGRHNDI 378
            .||...|....|.|.::...|     :|...|:  ..|...|......|.:    |:.|
Yeast   378 THKYGFAPKGSSVIMYRNSDL-----RMHQYYVNPAWTGGLYGSPTLAGSRPGAIVVGC------ 431

  Fly   379 FKLWLQWRAKGTEGFEQQ---------------QDRLMEL----------VQYQLK--RIREQSD 416
               |......|..|:.:.               |:.:.:|          :.:..|  .|.|.||
Yeast   432 ---WATMVNMGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSD 493

  Fly   417 R-------FHLILEPECVNVSFWYVPKRLRGVPHDAKKEVELGKICPIIKGRMMQ-KGTLMVGYQ 473
            |       |:.:.:|..::::|..:...:            :.:||.|::..:.: |........
Yeast   494 RLSKKGWHFNALQKPVALHMAFTRLSAHV------------VDEICDILRTTVQELKSESNSKPS 546

  Fly   474 PDDRRPNF-FRSIISSAAVNEADVDFMLDEIHRLG 507
            ||.....: ....:.:|.|.:..:...||.:::||
Yeast   547 PDGTSALYGVAGSVKTAGVADKLIVGFLDALYKLG 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_523914.2	Pyridoxal_deC	64..434	CDD:395219	82/451 (18%)
DPL1	NP_010580.1	DOPA_deC_like	169..532	CDD:99743	78/419 (19%)