Protein Alignment Gad1 and Gadl1

DIOPT Version :10

• Sequence 1: NP_523914.2
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001382689.1
• Gene: Gadl1 / 73748
• MGIID: 1920998
• Length: 522
• Species: Mus musculus
• Alignment Length: 492
• Identity: 222/492 - (45%)
• Similarity: 319/492 - (64%)
• Gaps: 12/492 - (2%)

  Fly    27 VTAGPET-----REFLLKVIDVLLDFV--KATNDRNEKVLDFHHPEDMKRLLDLDVPDRALPLQQ 84
            |..||:|     .:|:.:...::::.|  ||| |.||||.::..||.:::||||::.|......:
Mouse    35 VLNGPQTDVKAGEKFVEEACRLIMEEVVLKAT-DVNEKVCEWQPPEQLRQLLDLEMRDTGESQDK 98

  Fly    85 LIEDCATTLKYQVKTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMENVVLTK 149
            |::.|...:.:.|||.||.|||||..|||..|:|...:|...|.:::|||::|||:|:|..||.|
Mouse    99 LLKLCQDVIHFSVKTNHPRFFNQLYAGLDYYSLAARIITEALNPSIYTYEVSPVFLLVEEAVLKK 163

  Fly   150 MREIIGWSGGDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPGTLVMFTSDQCHYSIKSCA 214
            |.|.:||..||.|..||||:||:.|...||::..|:.||.|..||| .|::|||.:||||:|..|
Mouse   164 MIECVGWKEGDGIFNPGGSVSNMCAMNLARYRHCPDIKEKGLSGLP-RLILFTSAECHYSMKKAA 227

  Fly   215 AVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAFDDINTIADIC 279
            :..|:||.:...|.:|..||||..:||:.|.:.:.:|.:||.|.||:|||||||||.::.||::|
Mouse   228 SFLGIGTQNVYFVETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLGAFDPLDEIAEVC 292

  Fly   280 QKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTWNPHKLMGALLQCSTIHFKE-DGLLIS 343
            :::..|:|:||:|||..|:|||||. ...|:.|||||.|||||::.|.:|||.:..|: ..||..
Mouse   293 ERHGLWLHVDASWGGSALVSRKHRR-LLHGIHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKK 356

  Fly   344 CNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQWRAKGTEGFEQQQDRLMELVQYQL 408
            |....|.|||..||.||:|||||||.|||.|..|.||.|:.|:|.||.|.|::.:|...|.:|.:
Mouse   357 CYSAKATYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYLV 421

  Fly   409 KRIREQSDRFHLILEPECVNVSFWYVPKRLRGVPHDAKKEVELGKICPIIKGRMMQKGTLMVGYQ 473
            ..|::: :.|.|::|||..||.|||:|..||.:....:...:|..:.|.||.:||:||:||:|||
Mouse   422 DEIKKR-EGFKLLMEPEYTNVCFWYIPPSLREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQ 485

  Fly   474 PDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL 510
            |...:.||||.::.|..|:..|:||:||||..||.|:
Mouse   486 PHRGKVNFFRQVVISPQVSREDMDFLLDEIDSLGRDM 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_523914.2	Pyridoxal_deC	64..434	CDD:395219	174/370 (47%)
Gadl1	NP_001382689.1	GadA	76..521	CDD:439846	207/447 (46%)