Protein Alignment Gad1 and gadl1

DIOPT Version :10

• Sequence 1: NP_523914.2
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_012820293.1
• Gene: gadl1 / 733871
• XenbaseID: XB-GENE-5721903
• Length: 522
• Species: Xenopus tropicalis
• Alignment Length: 520
• Identity: 234/520 - (45%)
• Similarity: 327/520 - (62%)
• Gaps: 19/520 - (3%)

  Fly     1 MSLNPNGYKLSERTGKLTAYDLMPTTVTAGP-----ETREFLLKVIDVLL-DFVKATNDRNEKVL 59
            |.::.|  |...|..|..|. |:...|..||     ...:|:..|..:|: :.|...:|.|:||.
 Frog    12 MEVDKN--KQETRPMKRNAV-LVDGVVLNGPIIDSSSGEKFVEDVYRILMNELVYKASDINQKVC 73

  Fly    60 DFHHPEDMKRLLDLDVPDRALPLQQLIEDCATTLKYQVKTGHPHFFNQLSNGLDLISMAGEWLTA 124
            ::..||.:|:||||::.|...|.::|::.|...:||.|||.||.|||||..|:|..|:|..::|.
 Frog    74 EWQEPEQLKKLLDLNIKDNGEPHEKLLQLCKNVIKYSVKTSHPRFFNQLYAGMDHYSLAARFITE 138

  Fly   125 TANTNMFTYEIAPVFILMENVVLTKMREIIGWSGGDSILAPGGSISNLYAFLAARHKMFPNYKEH 189
            ..|.:::|||::|||||.|..:|.||.|.:||..||.|.:||||:||:||...||:|..|:.|:.
 Frog   139 ALNPSVYTYEVSPVFILTEEAILKKMIEFLGWKEGDGIFSPGGSVSNMYAVNLARYKYCPDIKQK 203

  Fly   190 GSVGLPGTLVMFTSDQCHYSIKSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIP 254
            |....| .||||||::||||:|..||..|:||::...|.:|:.||||..|||..|...|.:..:|
 Frog   204 GLSSAP-RLVMFTSEECHYSMKKAAAFLGIGTENVYFVKTDDRGKMIPEELENQIQRAKKEAAVP 267

  Fly   255 FFVNATAGTTVLGAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRKHR---HPRFTGVERADSV 316
            |.|:||:|||||||||.::.||:||:|:..|.|:||:|||..|||:|:|   |    |:.|||||
 Frog   268 FLVSATSGTTVLGAFDPLDDIANICEKHKLWFHVDASWGGSALMSQKYRKCLH----GIHRADSV 328

  Fly   317 TWNPHKLMGALLQCSTIHFKED-GLLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFK 380
            .|||||::.|.:||..:..::: |||..|:...|.|||..||.||:.||||||.|||.|..|.||
 Frog   329 AWNPHKMLMAGIQCCALLVRDNSGLLKRCHSAEATYLFQQDKFYDVQYDTGDKSIQCSRRADAFK 393

  Fly   381 LWLQWRAKGTEGFEQQQDRLMELVQYQLKRIREQSDRFHLILEPECVNVSFWYVPKRLRGVPHDA 445
            .|:.|:|.||.|.|::.:|.:.|.:|....|::: |.|.|:.|||..|..|||:|...|.:....
 Frog   394 FWMMWKALGTTGLEERINRALALTRYLASEIKKR-DGFELLWEPEYANTCFWYIPPSFRNMEKGP 457

  Fly   446 KKEVELGKICPIIKGRMMQKGTLMVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL 510
            :...:...:.|.||.|||:||::||||||...:.||||.|:.|..|:..|:||:||||.|||.||
 Frog   458 EYWRKFSNVAPTIKERMMKKGSMMVGYQPHRDKVNFFRHIVISPQVSREDMDFVLDEIERLGRDL 522

  Fly   511  510
             Frog   523  522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_523914.2	Pyridoxal_deC	64..434	CDD:395219	180/373 (48%)
gadl1	XP_012820293.1	GadA	76..521	CDD:439846	214/450 (48%)