DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gad1 and CG5618

DIOPT Version :9

Sequence 1:	NP_001261396.1	Gene:	Gad1 / 38484	FlyBaseID:	FBgn0004516	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	198/463 - (42%)
Similarity:	280/463 - (60%)	Gaps:	10/463 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 EKVLDFHHPEDMKRLLDLDVPD-RALPLQQLIEDCATTLKYQVKTGHPHFFNQLSNGLDLISMAG 119
            :|::.|..|:.:|.|::|.|.: ....|.::.|.|...:.|.|||.|..|.|||...||...:||
  Fly    48 QKIVPFLQPDKLKELINLKVRETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAG 112

  Fly   120 EWLTATANTNMFTYEIAPVFILMENVVLTKMREIIGWSGGDSILAPGGSISNLYAFLAARHKMFP 184
            ..:|...|.:.:|||:||||.|:|..|:..:.::.|:..||.|.|||||.||:|..:.||:|:.|
  Fly   113 ALVTEAMNGSTYTYEVAPVFSLIETEVIATICKLAGYKEGDGIFAPGGSTSNMYGMVLARYKIAP 177

  Fly   185 NYKEHGSVGLPGTLVMFTSDQCHYSIKSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKA 249
            ..|..|..|: ..||:||||:.|||....|...|||:.:|:.|.::|.|:|:..:||..|.|.||
  Fly   178 EVKTSGMFGM-RPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAEAKA 241

  Fly   250 KGDIPFFVNATAGTTVLGAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERAD 314
            :|..|||||.||||||||||||||..||:.:::..|:|:||..||..|:|.|:| ....|:|||:
  Fly   242 RGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAALLSAKNR-SLIAGLERAN 305

  Fly   315 SVTWNPHKLMGALLQCSTIHFKEDG-LLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDI 378
            |.:|||||.:||.||||....:|.| ||..||...|.|||..||.||:|||||:|.:||||..|.
  Fly   306 SFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFYDVSYDTGNKSVQCGRKIDA 370

  Fly   379 FKLWLQWRAKGTEGFEQQQDRLMELVQYQLKRIREQSDRFHLIL-EPECVNVSFWYVPKRLRGVP 442
            ||.||..:|:|...:....|..:.:.:....::|::.|||.|:: |.|..||.||::||.:|...
  Fly   371 FKFWLMLKARGYGKYGLMVDHAIHIARLLEGKLRQRGDRFRLVIPEHEYSNVCFWFIPKAMRVSS 435

  Fly   443 HDAKKE--VELGKICPIIKGRMMQKGTLMVGYQPDDRR--PNFFRSIISSAAV-NEADVDFMLDE 502
            .:...|  ..|..:.|.||.:|...||||:||.|...:  .||||.:.:...: ...::||:|||
  Fly   436 EEETPEWWSRLYTVAPKIKEQMAHSGTLMIGYSPLKAKNLGNFFRMVFTCFPILKSKELDFILDE 500

  Fly   503 IHRLGDDL 510
            |.|||:.:
  Fly   501 IERLGEKI 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_001261396.1	Pyridoxal_deC	64..434	CDD:395219	167/372 (45%)
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	180/408 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100596
Panther	1	1.100	-	-	P	PTHR45677
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.820