DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gad1 and amd

DIOPT Version :9

Sequence 1:	NP_001261396.1	Gene:	Gad1 / 38484	FlyBaseID:	FBgn0004516	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_476592.1	Gene:	amd / 35188	FlyBaseID:	FBgn0000075	Length:	510	Species:	Drosophila melanogaster

Alignment Length:	499	Identity:	124/499 - (24%)
Similarity:	221/499 - (44%)	Gaps:	49/499 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ETREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDLDVPDRALPLQQLIEDCATTLKYQ 96
            |.|||....||.:.|:::  |.|::.||....|..:..||..::|:.....:.::.|.:..:|..
  Fly     5 EFREFGKAAIDYIADYLE--NIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIKPG 67

  Fly    97 V---KTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMENVVLTKMREII---- 154
            :   ::.|.|.:...|....  |:.||.|.:......|::..:|....:|.||:..:.:.:
  Fly    68 LTHWQSPHMHAYYPTSTSYP--SIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPA 130

  Fly   155 -------GWSGGDSILAPGGSISNLYAFLAARHKMFPNYKE-HGSVG---LPGTLVMFTSDQCHY 208
                   |..||  ::....|.:.|.|.||||.:...||:| |..:.   :.|.||.::|||.:.
  Fly   131 HFQHASDGPGGG--VIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNS 193

  Fly   209 SIKSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAFDDIN 273
            .|:....:..:...   ::|:.|...:....|...|.|..|.|.||....||.|||...|:|||.
  Fly   194 CIEKAGVLAAMPIR---LLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIE 255

  Fly   274 TIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTWNPHKLMGALLQCSTIHFKED 338
            :::.:|:::..|:|:|||:.||.....:....| .|::|.||:.:|.||.|.....||.:..::.
  Fly   256 SLSAVCEEFKVWLHVDAAYAGGAFALEECSDLR-KGLDRVDSLNFNLHKFMLVNFDCSAMWLRDA 319

  Fly   339 GLLISCNQMSAEYLFMTDKQYDISY--DTGDKVIQCGRHNDIFKLWLQWRAKGTEGFEQQQDRLM 401
            ..::  :..:.:.:::..|....|.  |.....|..||.....|:|:.:|..|.||......:.:
  Fly   320 NKVV--DSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHI 382

  Fly   402 ELVQYQLKRIREQSDRFHLILEPECVNVSFWYVPKRLRGVPHDAKKEVELGKICPIIKGRMMQKG 466
            ||.: |.:::..:..||.|:            .|:.|..|....|.:.|:  ...:::..|.:|.
  Fly   383 ELAK-QFEQLVLKDSRFELV------------APRALGLVCFRPKGDNEI--TTQLLQRLMDRKK 432

  Fly   467 TLMVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL 510
            ..||..:...|:  |.|.::.......:|:||...||.....||
  Fly   433 IYMVKAEHAGRQ--FLRFVVCGMDTKASDIDFAWQEIESQLTDL 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_001261396.1	Pyridoxal_deC	64..434	CDD:395219	94/389 (24%)
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:278699	97/401 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810