Protein Alignment Gad1 and hdl-2

DIOPT Version :9

• Sequence 1: NP_001261396.1
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_501539.3
• Gene: hdl-2 / 182464
• WormBaseID: WBGene00006409
• Length: 611
• Species: Caenorhabditis elegans
• Alignment Length: 472
• Identity: 86/472 - (18%)
• Similarity: 172/472 - (36%)
• Gaps: 105/472 - (22%)

  Fly     9 KLSERTGKLTAYDLMPTTVTAGPETREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDL 73
            ||.|..||                 .|| :|.:.:::.|:....|.:.|.......:.....:.:
 Worm   109 KLQEPIGK-----------------NEF-IKCMSLVVQFINDYFDESHKQPVIPENDVNSSRIHV 155

  Fly    74 DVPDRALPLQQLIEDCATTLKYQV-----KTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTY 133
            .||::|..|.::::|    ||..|     .|.||.:..:.: |..|..:....::|....::
 Worm   156 KVPEKAEELTEILKD----LKEIVIPNICHTHHPRYHAKFA-GKSLADLVASTISAALGHDV--- 212

  Fly   134 EIAPVFILMENVV----------------LTKMREIIGWSGGDSILAPGGSISNLYAFLAARHKM 182
            ..:|:...:|.::                |.::|:.|    |.....|.....::......:.:.
 Worm   213 NSSPIIESIERIICKWLSTSMAIPQIKSSLGELRDPI----GTVFYTPCDVFISVIRHAIEKFEK 273

  Fly   183 FPNYKEHGSVGLPGTLVMFTSDQCHYSIKSCAAVCGLGTDHCIVVPSDEHGKMITS-----ELER 242
            ..:.||...   ....:::.||.....:|.....|.:....  |:..:::|..:||     ::|:
 Worm   274 TDSGKERSK---NADYIVYCSDDSQVPLKEPCISCRVKLRK--VITDEKNGSGMTSANLLKQMEK 333

  Fly   243 LILERKAKGDIPFFVNATAGTTVLGAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRF 307
            .|    |:|..|..:.|..|:..:.|.|:|..:..:.:....|:|:||::.|...:....|:
 Worm   334 DI----ARGFTPLVIIANYGSANIAANDEIWDLVTVSRSKKIWLHLDASYAGCEWLDSNSRN--- 391

  Fly   308 TGVERADSVTWNPHKLMGAL----LQCSTIHFKEDG---LLISCNQMSAEYLFMTDKQYDISYDT 365
                       |.|.|:..:    :.||:: |...|   ::.||.::..:
 Worm   392 -----------NVHALISEVHSVHITCSSL-FPYSGRISVVWSCEKLELD--------------- 429

  Fly   366 GDKVIQCGRHNDIFKLWLQWRAKGTEGFEQQQDRLMELVQYQLKRIREQSDRFHLILEPECVNVS 430
            |.|::. |.|.  .:||:..|..|.....:...|.:.|.....:|:...|..|.:....|.....
 Worm   430 GAKILY-GEHP--IRLWILIRLHGIRSIREAVKRKIILGNAFSERMSHHSQLFEMHHTNEHGVTV 491

  Fly   431 FWYVPKRLRGVPHDAKK 447
            |.|..|:::....|..|
 Worm   492 FQYKNKKIKDRTEDTNK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_001261396.1	Pyridoxal_deC	64..434	CDD:395219	71/402 (18%)
hdl-2	NP_501539.3	AAT_I	125..527	CDD:302748	78/438 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810