Protein Alignment Gad1 and Hdc

DIOPT Version :10

• Sequence 1: NP_523914.2
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_006498847.1
• Gene: Hdc / 15186
• MGIID: 96062
• Length: 681
• Species: Mus musculus
• Alignment Length: 454
• Identity: 108/454 - (23%)
• Similarity: 183/454 - (40%)
• Gaps: 73/454 - (16%)

  Fly    22 LMPTTVTAGPETREFLL---KVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDLDVPDRALPLQ 83
            |..||:    ..|.|:|   :::|.:..::....:|  :|.....|..::..|....|:......
Mouse    23 LSTTTL----RVRCFILSGKEMVDYISQYLSTVRER--QVTPNVQPGYLRAQLPASAPEEPDSWD 81

  Fly    84 QLIEDCATTLKYQV---KTGHPH-FFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMEN 144
            .:..|....:...|   ::.|.| ::..|::...|:   |:.|....|...||:..:|....:|.
Mouse    82 SIFGDIERVIMPGVVHWQSPHMHAYYPALTSWPSLL---GDMLADAINCLGFTWASSPACTELEM 143

  Fly   145 VVLTKMREIIGW----------SGGDSILAPGGSISNLYAFLAARHKMF-------PNYKEHGSV 192
            .::..:.:::|.          |.|..:|....|.|.|.|.||||....       |:..|.
Mouse   144 NIMDWLAKMLGLPEYFLHHHPSSRGGGVLQSTVSESTLIALLAARKNKILAMKACEPDANES--- 205

  Fly   193 GLPGTLVMFTSDQCHYSIKSCAAVCGLGTDHCIV----VPSDEHGKMITSELERLILERKAKGDI 253
            .|...||.:||||.|.|::....:       .:|    :|.|::..:....|::.|.|.|.:|.:
Mouse   206 SLNARLVAYTSDQAHSSVEKAGLI-------SLVKIRFLPVDDNFSLRGEALQKAIEEDKQQGLV 263

  Fly   254 PFFVNATAGTTVLGAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTW 318
            |.||.||.|||.:.|||.::.:..||.....|:|:|||:.|...:..:.| ....|:|.|||.|:
Mouse   264 PVFVCATLGTTGVCAFDRLSELGPICASEGLWLHVDAAYAGTAFLCPELR-GFLEGIEYADSFTF 327

  Fly   319 NPHKLMGALLQCSTIHFKEDGLLISCNQMSAEYLFMTDKQYDISYDTGDKV------IQCGRHND 377
            ||.|.|       .:||...|..:. ::...:..|..:..|....::|...      |...|...
Mouse   328 NPSKWM-------MVHFDCTGFWVK-DKYKLQQTFSVNPIYLRHANSGAATDFMHWQIPLSRRFR 384

  Fly   378 IFKLWLQWRAKGTEGFEQQQDRLMELVQYQLKRIR-----EQSDRFHL------ILEPECVNVS 430
            ..|||...|:.|.:..:.......|:.:|....:|     |...:.||      :..|.|:..|
Mouse   385 SIKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRSDPSFEIPAKRHLGLVVFRLKGPNCLTES 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_523914.2	Pyridoxal_deC	64..434	CDD:395219	99/409 (24%)
Hdc	XP_006498847.1	Pyridoxal_deC	62..440	CDD:395219	96/399 (24%)