Protein Alignment Gad1 and LOC1280045

DIOPT Version :10

• Sequence 1: NP_523914.2
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_319840.3
• Gene: LOC1280045 / 1280045
• VectorBaseID: AGAMI1_013878
• Length: 545
• Species: Anopheles gambiae
• Alignment Length: 527
• Identity: 130/527 - (24%)
• Similarity: 220/527 - (41%)
• Gaps: 72/527 - (13%)

  Fly    17 LTAYDLMPT-----TVTAGPETREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDLDVP 76
            ||.:..||.     |....||.::|..:::|.:.::::  |.|:.:||....|..::.|:..:.|
Mosquito    52 LTNFIKMPVPCETRTEMQAPEFKDFAKEMVDYISNYLE--NIRDRRVLPTVQPGYLRPLIPDEAP 114

  Fly    77 DRALPLQQLIEDCATTLKYQVKTGH-PHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFI 140
            .:....::::.|....:...|...| |.|...........::..:.|:.......||:..:|...
Mosquito   115 QQPEKWEEVMADVERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACT 179

  Fly   141 LMENVVLT---KM----REIIGWSGGD--SILAPGGSISNLYAFLAARHKMFPNYKEH----GSV 192
            .:|.|:|.   ||    :|.:..|||.  .::....|.:.|.|.|.|:.|.....||.    ...
Mosquito   180 ELEVVMLDWLGKMLDLPKEFLACSGGQGGGVIQGTASEATLVALLGAKAKAMKRVKEEHPDWDDN 244

  Fly   193 GLPGTLVMFTSDQCHYSIKSCAAVCGL---GTDHCIVVPSDEHGKMITSELERLILERKAKGDIP 254
            .:...||.:||:|.|.|::....:.|:   |      :.:||:.|:....||:.|.|....|.||
Mosquito   245 TIVSKLVGYTSNQSHSSVERAGLLGGVKLRG------LKADENLKLRGETLEQAIKEDLDAGLIP 303

  Fly   255 FFVNATAGTTVLGAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTWN 319
            |:|.||.|||...|||.::.|..:..:||.|:|:|||:.|...:..::|: ...|:|.|||..:|
Mosquito   304 FYVVATLGTTNTCAFDRLDEIGPVANQYNVWVHVDAAYAGSAFICPEYRY-LMKGIETADSFNFN 367

  Fly   320 PHKLMGALLQCSTIHFKEDGLLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQ 384
            |||.|.....||.:..||...::  |..:.:.|::.......:.|.....|..||.....|||..
Mosquito   368 PHKWMLVNFDCSAMWLKEPYWIV--NAFNVDPLYLKHDMQGSAPDYRHWQIPLGRRFRALKLWFV 430

  Fly   385 WRAKGTEGFEQQQDRLMELVQYQLKRIREQSDRFHLILEPECVNVSFWYVPKRLRGVPHDAKKEV 449
            .|..|.:..:....|.....: |.:.:....|||.:.                         .||
Mosquito   431 LRLYGVDNLQAHIRRHCGFAK-QFEALCRADDRFEIF-------------------------GEV 469

  Fly   450 ELGKICPIIKG----------RMMQKGTL-MVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEI 503
            .:|..|..:||          |:..:|.: :|..:.:|  ..|.|..:.|.....||:|:...|:
Mosquito   470 AMGLACFRLKGTNELSEALLKRINGRGNIHLVPSKVND--VYFLRMAVCSRFTEPADIDYSWKEV 532

  Fly   504 HRLGDDL 510
            ....|:|
Mosquito   533 AAAADEL 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_523914.2	Pyridoxal_deC	64..434	CDD:395219	98/386 (25%)
LOC1280045	XP_319840.3	None