Protein Alignment Gad1 and Hdc

DIOPT Version :10

• Sequence 1: NP_523914.2
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_061513412.1
• Gene: Hdc / 1279960
• VectorBaseID: AGAMI1_008036
• Length: 934
• Species: Anopheles gambiae
• Alignment Length: 489
• Identity: 116/489 - (23%)
• Similarity: 196/489 - (40%)
• Gaps: 94/489 - (19%)

  Fly    39 KVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDLDVPDRALPLQQLIEDCATTLKYQV---KTG 100
            :::|.:.|:::  |.|..:||....|..|:.|:....|......:.:..|....:...:   ::.
Mosquito    12 EMVDYIADYLQ--NIRERRVLPDVQPGYMRSLIPESAPLEGERWENIFADVERVIMPGITHWQSP 74

  Fly   101 HPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMENVVLTKMREII----------G 155
            |.|.:....|...  |:.|:.|....|...||:..:|....:|::|:..:.::|          |
Mosquito    75 HMHAYFPALNSFP--SLLGDMLADAINCLGFTWASSPACTELESIVMNWLGKMIGLPDSFLHLPG 137

  Fly   156 WSGGDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPG--------TLVMFTSDQCHYSIKS 212
            .|.|..::....|.:.|...||.|......:.||    .||        .||.:.|||.|.|::.
Mosquito   138 TSMGGGVIQTTASEATLVCLLAGRTMAITRFHEH----TPGLQDAEINARLVAYCSDQAHSSVEK 198

  Fly   213 CAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAFDDINTIAD 277
            .|.:   |......:.||:...:....|...|.|...:|.|||:|.||.|||...|||.::.|::
Mosquito   199 AALI---GLVRMRFIESDDQLSLRGDALREAIEEDIKQGLIPFWVCATLGTTGACAFDHLDEISE 260

  Fly   278 ICQKYNCWMHIDAAWGGGLLMSRKHRHPRF----TGVERADSVTWNPHKLMGALLQCSTIHFKED 338
            :|.:||.|:|:|||:.|...:.     |.|    .|:|:|||:.:||.|.:.....|:.:..|..
Mosquito   261 VCARYNIWLHVDAAYAGSAFIC-----PEFRVWLKGIEKADSIAFNPSKWLMVHFDCTAMWLKNS 320

  Fly   339 GLLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQWRAKGTEG----------- 392
            |.|  ....:...|::..:...:|.|.....|...:.....|||...|:.||.|
Mosquito   321 GAL--HRTFNVAPLYLQHENSGLSIDYMHWQIPLSKRFRALKLWFVLRSFGTRGLQKHIREGVRL 383

  Fly   393 -------------FEQQQDRLMELVQYQLKRIREQSDRFHLILEPECVNVSFWYVPKRL--RGVP 442
                         ||....|.:.:|.:::|...|.:::                :.|||  ||..
Mosquito   384 AQKFEALILADHRFEIPATRHLGMVVFRIKGENELTEK----------------LLKRLNQRGHM 432

  Fly   443 HDAKKEVELGKICPIIKGRMMQKGTLMVGYQPDD 476
            |         .:...:|||.:.:.|:...|..:|
Mosquito   433 H---------AVPASLKGRYVIRFTVTSTYTTND 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_523914.2	Pyridoxal_deC	64..434	CDD:395219	98/418 (23%)
Hdc	XP_061513412.1	None