Protein Alignment Gad1 and gad1.1

DIOPT Version :9

• Sequence 1: NP_001261396.1
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_004917766.1
• Gene: gad1.1 / 100496528
• XenbaseID: XB-GENE-1011699
• Length: 590
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 284/502 - (56%)
• Similarity: 369/502 - (73%)
• Gaps: 13/502 - (2%)

  Fly    17 LTAYDLMPTTVTAGPE-TREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLD---LDVPD 77
            |.|.||:|  ...|.| |.:|||:|:|:||::|:.|.||:.||||||||..:...::   |::.|
 Frog    94 LFARDLLP--AKNGEEFTMQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGIEGFNLELSD 156

  Fly    78 RALPLQQLIEDCATTLKYQVKTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILM 142
            ....|:|::.||..||||.|:||||.||||||.|||:|.:||||||:|||||||||||||||:||
 Frog   157 NPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLM 221

  Fly   143 ENVVLTKMREIIGWS--GGDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPGTLVMFTSDQ 205
            |.:.|.||||||||:  .||.|.:|||:|||:|:.:|||:|.||..|..|...:| .||:|||:.
 Frog   222 EQITLRKMREIIGWTEKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVP-RLVLFTSEH 285

  Fly   206 CHYSIKSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAFD 270
            .|||||...|..|.|:::.|:|.::|.||:|.::||..|||.|.||.:|.:|||||||||.||||
 Frog   286 SHYSIKKTGAALGFGSENVIMVKTNERGKIIPADLEAKILEAKQKGYVPLYVNATAGTTVYGAFD 350

  Fly   271 DINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTWNPHKLMGALLQCSTIHF 335
            .|:.|||||:|||.|:|:||||||||||||:||| :..|:|||:||||||||:||.|||||.|..
 Frog   351 PISEIADICEKYNLWLHVDAAWGGGLLMSRRHRH-KLDGIERANSVTWNPHKMMGVLLQCSAILL 414

  Fly   336 KEDGLLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQWRAKGTEGFEQQQDRL 400
            :|.|:|..||||.|.|||..|||||||||||||.||||||.||||.||.|:||||.|||.|.::.
 Frog   415 REKGILQGCNQMCAGYLFQQDKQYDISYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFEAQINKC 479

  Fly   401 MELVQYQLKRIREQSDRFHLILE--PECVNVSFWYVPKRLRGVPHDAKKEVELGKICPIIKGRMM 463
            :||.:|...:|..: :.|.::..  ||..||.|||:|..|||:|::.:|:.:|.::.|.||..||
 Frog   480 LELAEYLYSKIYNR-EGFEMVFNGVPEHTNVCFWYIPPSLRGMPNNEEKQEKLHRVAPKIKALMM 543

  Fly   464 QKGTLMVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL 510
            :.||.||||||...:.||||.:||:.|..::|:||:::||.|||.:|
 Frog   544 ESGTTMVGYQPQGDKANFFRMVISNPAATKSDIDFLVEEIERLGQEL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_001261396.1	Pyridoxal_deC	64..434	CDD:395219	221/376 (59%)
gad1.1	XP_004917766.1	Pyridoxal_deC	140..514	CDD:395219	221/376 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	460	1.000	Domainoid score	I480
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H635
Inparanoid	1	1.050	580	1.000	Inparanoid score	I1011
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	1	1.000	-	-		otm48085
Panther	1	1.100	-	-	O	PTHR45677
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X464
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160