Protein Alignment Gad1 and gad2

DIOPT Version :10

• Sequence 1: NP_523914.2
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_017950266.1
• Gene: gad2 / 100493806
• XenbaseID: XB-GENE-976598
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 498
• Identity: 274/498 - (55%)
• Similarity: 358/498 - (71%)
• Gaps: 8/498 - (1%)

  Fly    17 LTAYDLMPTTVTAGPETREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDLDVPDRALP 81
            |.:.||:|:....| .|..||..||||||.:|..|.||:.||:|||:|.::.:..:.::.::...
 Frog    95 LYSTDLLPSKNGEG-VTMTFLQDVIDVLLQYVVQTFDRSTKVIDFHYPNELLQAYNWELSEQPQS 158

  Fly    82 LQQLIEDCATTLKYQVKTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMENVV 146
            |..::.:|.|||||.:|||||.:|||||.|||::.:|.:|||:|||||||||||||||:|:|.|.
 Frog   159 LDGILLNCKTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVT 223

  Fly   147 LTKMREIIGWSG--GDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPGTLVMFTSDQCHYS 209
            |.||||:|||.|  ||.|.:|||:||||||.|.||.||||..||.|...|| .||.|||:..|:|
 Frog   224 LKKMREMIGWPGGSGDGIFSPGGAISNLYAMLIARFKMFPEVKEKGMAALP-RLVAFTSEHSHFS 287

  Fly   210 IKSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAFDDINT 274
            :|..||..|:|||..|::.:||.|::|.|:|||.|:|.|..|.:||||:|||||||.||||.:.:
 Frog   288 VKKGAAALGIGTDSVILIKADERGRLIPSDLERRIIEAKQNGYVPFFVSATAGTTVYGAFDPLVS 352

  Fly   275 IADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTWNPHKLMGALLQCSTIHFKEDG 339
            |||||:||..|||:||||||||||||||:. :..|.:||:||||||||:||..||||.:..:|:|
 Frog   353 IADICKKYRIWMHVDAAWGGGLLMSRKHKW-KLNGADRANSVTWNPHKMMGVPLQCSALLVREEG 416

  Fly   340 LLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQWRAKGTEGFEQQQDRLMELV 404
            |:.:||||.|.|||..||.||:|||||||.:|||||.|||||||.||||||.|||...|:.:||.
 Frog   417 LMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDIFKLWLMWRAKGTTGFEAHIDKCLELS 481

  Fly   405 QYQLKRIREQSDRFHLILE--PECVNVSFWYVPKRLRGVPHDAKKEVELGKICPIIKGRMMQKGT 467
            :|...:|:.: :.:.:::|  |:..||.|||||..||.:..:.::...|.|:.||||.|||:.||
 Frog   482 EYLYNKIKNR-EGYEMVIEGKPQHTNVCFWYVPPSLRNMEDNEERMNRLSKVAPIIKARMMEYGT 545

  Fly   468 LMVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL 510
            .||.|||...:.||||.:||:.|....|:||:::||.|||.||
 Frog   546 TMVSYQPHGDKGNFFRMVISNPAAAHQDIDFLIEEIERLGQDL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_523914.2	Pyridoxal_deC	64..434	CDD:395219	213/373 (57%)
gad2	XP_017950266.1	Pyridoxal_deC	141..512	CDD:395219	213/373 (57%)