DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11593 and URK1

DIOPT Version :9

Sequence 1:	NP_001261392.1	Gene:	CG11593 / 38477	FlyBaseID:	FBgn0035488	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_014409.1	Gene:	URK1 / 855746	SGDID:	S000005295	Length:	501	Species:	Saccharomyces cerevisiae

Alignment Length:	235	Identity:	45/235 - (19%)
Similarity:	82/235 - (34%)	Gaps:	72/235 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ADDVLPT----APEKNILKLEQAKQDHDKEELEFKTTSALDNRILRPELLPMEAMPQRHNIIERT 93
            ||.::|:    |...|::      .:|.|.:||.|:     |..|| ||:.:.:.|.: :::.|.
Yeast   234 ADAIIPSMSDNATAVNLI------INHIKSKLELKS-----NEHLR-ELIKLGSSPSQ-DVLNRN 285

  Fly    94 LANSHPLMSPTNTDSDSEPFQLKKQEK---------------------QLPRSNFPDVVPTTETV 137
            :.:..|   |||.........|.|...                     .:|.::...:.|...|:
Yeast   286 IIHELP---PTNQVLSLHTMLLNKNLNCADFVFYFDRLATILLSWALDDIPVAHTNIITPGEHTM 347

  Fly   138 QVKNNLNQCR---------NKPQDAKVSLLRANSPDI----LSSESDADVS------QYLAAVES 183
            :   |:..|:         .:..|..:..||...|:|    |..:||:...      ::|.....
Yeast   348 E---NVIACQFDQVTAVNIIRSGDCFMKSLRKTIPNITIGKLLIQSDSQTGEPQLHCEFLPPNIE 409

  Fly   184 NFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSISNHSFD 223
            .|..|.||         ....:.|...|.::..:.:|..|
Yeast   410 KFGKVFLM---------EGQIISGAAMIMAIQVLLDHGID 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11593	NP_001261392.1	BNIP2	<293..342	CDD:289278
CG11593	NP_001261392.1	CRAL_TRIO_2	345..475	CDD:290435
URK1	NP_014409.1	udk	69..260	CDD:272977	7/31 (23%)
URK1	NP_014409.1	Upp	280..501	CDD:223113	29/176 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900