DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11593 and atcaya

DIOPT Version :9

Sequence 1:	NP_001261392.1	Gene:	CG11593 / 38477	FlyBaseID:	FBgn0035488	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	XP_021325197.1	Gene:	atcaya / 565827	ZFINID:	ZDB-GENE-070705-185	Length:	367	Species:	Danio rerio

Alignment Length:	339	Identity:	124/339 - (36%)
Similarity:	195/339 - (57%)	Gaps:	30/339 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 DAKVSLLRANSPDILSSESDADVSQYLAAVESNFQSVSLM--PNGNGKKSKRSTALPGGEDISSL 214
            :|:...|..:.|..|.:|.|.|.|..|:...::..:..|:  ..|.|...||.|.:....:: ||
Zfish    14 EARDEWLDDDFPRPLPAEGDMDSSCALSDGRTSPPNSLLIGGAGGGGAHRKRRTLVAPDMNL-SL 77

  Fly   215 DS-----ISNHSFDDDEDIEHNLASLSPSSSLIDGLDGEDDDDDCEGPELLPDHDDDLELDLEFG 274
            |.     :|:...|..:|::.|          :|.::..|:.|..|    ...:.:|||.:.:..
Zfish    78 DQSEGSLLSDDFLDTPDDLDIN----------VDDIETPDETDSLE----FITNGNDLEWEDDTP 128

  Fly   275 LATTPTPNAPASATAASTLPQYTAAEERRDSRNWQKITLPDGRTREIDMRVIEPYKRVLSHGGYL 339
            :|:...|  ||.:.|.......|.|    :.|.|:.:.:.:...| |||:||.||.||:|||||.
Zfish   129 VASAKAP--PADSDADGEGVDGTGA----NGRLWRTVIIGEQEHR-IDMQVIRPYLRVISHGGYY 186

  Fly   340 KSGGQNAIVIFCACHLPDRSRADYSYVMDNLFLYVVKTLEQLVTDDYVLIYLHGGSNRRNVPPFP 404
             ..|.|||::|.||:|||.|..||.|:|:|||||||.:||.||.:||::||::||:.|..:|...
Zfish   187 -GEGLNAIIVFTACYLPDSSCPDYHYLMENLFLYVVSSLEMLVAEDYLIIYMNGGTPRSKMPGIS 250

  Fly   405 WLKRCYQLLDRRLRKSLKHMYLVHPTFWIKSLVWMARPFVSTKFWRKLVYVKSLEELGMHVVVEK 469
            |||:|||::||||||:||.:.:.||:::|::::.:::||:|.||..|:.||.|||||...|.::.
Zfish   251 WLKKCYQMIDRRLRKNLKSLIITHPSWFIRTVIAISKPFISVKFMNKIRYVHSLEELEKFVPMDH 315

  Fly   470 AAIPEKVKQYDAKR 483
            ..|||.:.||:.:|
Zfish   316 IHIPECILQYEEER 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11593	NP_001261392.1	BNIP2	<293..342	CDD:289278	19/48 (40%)
CG11593	NP_001261392.1	CRAL_TRIO_2	345..475	CDD:290435	66/129 (51%)
atcaya	XP_021325197.1	BNIP2	64..189	CDD:315215	41/147 (28%)
atcaya	XP_021325197.1	CRAL_TRIO_2	191..316	CDD:316255	64/124 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575200
Domainoid	1	1.000	160	1.000	Domainoid score	I4015
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3711
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330089at33208
OrthoFinder	1	1.000	-	-		FOG0001054
OrthoInspector	1	1.000	-	-		otm25376
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12112
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5755
SonicParanoid	1	1.000	-	-		X708
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.930