DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11593 and Bnipl

DIOPT Version :9

Sequence 1:	NP_001261392.1	Gene:	CG11593 / 38477	FlyBaseID:	FBgn0035488	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	XP_038958623.1	Gene:	Bnipl / 361994	RGDID:	1309478	Length:	376	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	117/397 - (29%)
Similarity:	194/397 - (48%)	Gaps:	90/397 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 SEP--------FQLKKQEKQLPRSNFPDVVP-------TTETVQ------VKNNLNQCRNKPQDA 153
            |||        .:||::.:.   ..||.::|       .||..|      ..::|..|..:|...
  Rat    43 SEPGAALSLGELELKEEWQD---EEFPRLLPEEASRSGDTEDAQRGSQAGTPSSLALCGQRPMRK 104

  Fly   154 KVSLLRANSPDILSSESDADVSQYLAAVESNFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSIS 218
            ::|     :|::..|.::.                                  .||:.:|....:
  Rat   105 RLS-----APELQLSLTEG----------------------------------AGENGASPSCSA 130

  Fly   219 NHSFDDDEDIEHNLASLSPSSSLIDGLDGEDDDDDCEGPELLPDHDDDLELDLEFGLATTPTPNA 283
            :.|.|...|:|            :|.|:...|.:     :|...|:.:.|.||       |....
  Rat   131 SSSSDASLDLE------------VDELETPSDSE-----QLDSGHEFEWEDDL-------PRAEG 171

  Fly   284 PASATAASTLPQYTAAE-ERRDSRNWQKITLPDGRTREIDMRVIEPYKRVLSHGGYLKSGGQNAI 347
            ..::.||..|.:....: ...|...| ::.....|.:.:||.:||||::||||||| ...|.||:
  Rat   172 LGASEAAERLGRGCVCDVAGEDGHRW-RVFRTGRREQRVDMTIIEPYRKVLSHGGY-HGDGLNAV 234

  Fly   348 VIFCACHLPDRSRADYSYVMDNLFLYVVKTLEQLVTDDYVLIYLHGGSNRRNVPPFPWLKRCYQL 412
            ::|.:|:||..|..:|:|||::||.|:|.|||.||.::|:|::|.||::|..|||..|:::||..
  Rat   235 ILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYHT 299

  Fly   413 LDRRLRKSLKHMYLVHPTFWIKSLVWMARPFVSTKFWRKLVYVKSLEELGMHVVVEKAAIPEKVK 477
            |||||||:|:.:.:||.|:::|:.:.:.|||:|:||.||:.::.||.||...:.:|:..|||.|:
  Rat   300 LDRRLRKNLRALVVVHATWYVKAFLALVRPFISSKFTRKIRFLDSLGELAQLISLEQVHIPEAVR 364

  Fly   478 QYDAKRH 484
            |.|...|
  Rat   365 QLDQDLH 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11593	NP_001261392.1	BNIP2	<293..342	CDD:289278	17/49 (35%)
CG11593	NP_001261392.1	CRAL_TRIO_2	345..475	CDD:290435	59/129 (46%)
Bnipl	XP_038958623.1	BNIP2	102..230	CDD:403629	38/192 (20%)
Bnipl	XP_038958623.1	CRAL_TRIO_2	232..369	CDD:404584	63/136 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336004
Domainoid	1	1.000	158	1.000	Domainoid score	I4011
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3469
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330089at33208
OrthoFinder	1	1.000	-	-		FOG0001054
OrthoInspector	1	1.000	-	-		otm45720
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12112
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X708
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.000