DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11593 and jupa

DIOPT Version :9

Sequence 1:	NP_001261392.1	Gene:	CG11593 / 38477	FlyBaseID:	FBgn0035488	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_571252.1	Gene:	jupa / 30415	ZFINID:	ZDB-GENE-991207-22	Length:	729	Species:	Danio rerio

Alignment Length:	286	Identity:	70/286 - (24%)
Similarity:	98/286 - (34%)	Gaps:	80/286 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 SDADVSQYL--------------AAVESNFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSISNH 220
            ||.|.::|.              |.|||..         |..:::|..|....|.:  ::....|
Zfish    37 SDDDGTEYSSKKFTYTTTFTENPAEVESQL---------NMTRAQRVRAAMFPETV--MEGSVIH 90

  Fly   221 SFDDDEDIEHNLASLS-PSSSL---IDGLDGEDDDDDCEG---PEL--LPDHDDDLELDLEFGLA 276
            |...|...:.|:..|: ||..|   |..|....||.:...   |||  |.:.:|.|.:: :..:.
Zfish    91 STQIDPSQQTNVQKLAEPSQQLKAAIVHLINYQDDAELATRAIPELTKLLNDEDQLVVN-KAAMI 154

  Fly   277 TTPTPNAPASATAASTLPQYTAAEERRDSRNWQKITLPDGRTREIDMRVIEPYKRVLSH--GGYL 339
            ........||..|....||..||..|.    .|..|  |..|......::..    |||  .|.|
Zfish   155 VNQLTRKEASRRALMQSPQMVAAVVRA----MQNTT--DMETTRATASILHN----LSHQREGLL 209

  Fly   340 ---KSGGQNAIVIFCACHLPDRSRADYSYVMDNLFLYVVKTLEQLVTDD---YVLIYLHGGSNRR 398
               ||||..|:|..            .|..||::..|.:.||..|:...   .:.:.|..|..|.
Zfish   210 AIFKSGGIPALVRM------------LSSPMDSVLFYAITTLHNLLLHQEGAKMAVRLADGLQRM 262

  Fly   399 NVPPFPWLKR-----------CYQLL 413
                .|.||:           |.|||
Zfish   263 ----VPLLKKSNPKFLAITTDCLQLL 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11593	NP_001261392.1	BNIP2	<293..342	CDD:289278	15/53 (28%)
CG11593	NP_001261392.1	CRAL_TRIO_2	345..475	CDD:290435	19/83 (23%)
jupa	NP_571252.1	armadillo repeat	133..158	CDD:293788	6/25 (24%)
		armadillo repeat	175..201	CDD:293788	7/35 (20%)
		ARM	209..328	CDD:237987	24/92 (26%)
		armadillo repeat	210..242	CDD:293788	12/43 (28%)
		armadillo repeat	250..286	CDD:293788	10/39 (26%)
		armadillo repeat	292..327	CDD:293788
		ARM	330..370	CDD:214547
		armadillo repeat	334..369	CDD:293788
		ARM	379..498	CDD:237987
		armadillo repeat	382..407	CDD:293788
		armadillo repeat	415..453	CDD:293788
		armadillo repeat	462..497	CDD:293788
		ARM	464..600	CDD:237987
		armadillo repeat	504..560	CDD:293788
		armadillo repeat	565..599	CDD:293788
		ARM	568..>645	CDD:237987
		armadillo repeat	607..637	CDD:293788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900