Protein Alignment CG11593 and BNIPL

DIOPT Version :10

• Sequence 1: NP_647851.3
• Gene: CG11593 / 38477
• FlyBaseID: FBgn0035488
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_612122.2
• Gene: BNIPL / 149428
• HGNCID: 16976
• Length: 357
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 124/374 - (33%)
• Similarity: 195/374 - (52%)
• Gaps: 58/374 - (15%)

  Fly   114 QLKK--QEKQLPRSNFPDVVPTTETVQVKNNLNQCRNKPQDAK-VSLLRANSPDILSSESDADVS 175
            :||:  |:::.||. .|:...|:|             .|:|.| .|...|.:|..|:......:.
Human    34 ELKEEWQDEEFPRL-LPEEAGTSE-------------DPEDPKGDSQAAAGTPSTLALCGQRPMR 84

  Fly   176 QYLAAVESNFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSISNHSFDDDEDIEHNLASLSPSSS 240
            :.|:|.|... |::..|..:|....:|..       ||.|..|:...|:       |.:.|.|..
Human    85 KRLSAPELRL-SLTKGPGNDGASPTQSAP-------SSPDGSSDLEIDE-------LETPSDSEQ 134

  Fly   241 LIDGLDGEDDDDDCEGPELLPDHDDDLELDLEFGLATTPTPNAPASATAASTLPQYTAAEERRDS 305
            |..|.:.|.:|                ||....||.|:.|    |.......:...|.    .|.
Human   135 LDSGHEFEWED----------------ELPRAEGLGTSET----AERLGRGCMWDVTG----EDG 175

  Fly   306 RNWQKITLPDGRTREIDMRVIEPYKRVLSHGGYLKSGGQNAIVIFCACHLPDRSRADYSYVMDNL 370
            .:|:...: ..|.:.:||.||||||:||||||| ...|.||:::|.:|:||..|..:|:|||::|
Human   176 HHWRVFRM-GPREQRVDMTVIEPYKKVLSHGGY-HGDGLNAVILFASCYLPRSSIPNYTYVMEHL 238

  Fly   371 FLYVVKTLEQLVTDDYVLIYLHGGSNRRNVPPFPWLKRCYQLLDRRLRKSLKHMYLVHPTFWIKS 435
            |.|:|.|||.||.::|:|::|.||::|..|||..|:::||:.|||||||:|:.:.:||.|:::|:
Human   239 FRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKA 303

  Fly   436 LVWMARPFVSTKFWRKLVYVKSLEELGMHVVVEKAAIPEKVKQYDAKRH 484
            .:.:.|||:|:||.||:.::.||.||...:.:::..|||.|:|.|...|
Human   304 FLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDLH 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11593	NP_647851.3	BNIP2	<293..342	CDD:463609	19/48 (40%)
		CRAL_TRIO_2	345..475	CDD:463965	58/129 (45%)
BNIPL	NP_612122.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..156		38/166 (23%)
		BNIP2	83..211	CDD:463609	45/168 (27%)
		CRAL_TRIO_2	213..350	CDD:463965	62/136 (46%)