Protein Alignment CG11594 and lyxK

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_418037.1
• Gene: lyxK / 948101
• ECOCYCID: EG12284
• Length: 498
• Species: Escherichia coli
• Alignment Length: 569
• Identity: 138/569 - (24%)
• Similarity: 225/569 - (39%)
• Gaps: 130/569 - (22%)

  Fly     6 FFVGVDVGTGSARAALVACDGRVLEQAVQTIQ--TWNPEPGYYNQSSDNIWQSICQVVKKVI--G 66
            :::|:|.|....:|.|...:||  |..||.:.  ..:|:||:..:....:||....|::.::  .
E. coli     4 YWLGLDCGGSWLKAGLYDREGR--EAGVQRLPLCALSPQPGWAERDMAELWQCCMAVIRALLTHS 66

  Fly    67 GVDKSKVKGIGFDATCSLVVLGPQGSPL-TVSKSGEAEQNIILWMDHRAEQ-----ETQEINAFK 125
            ||...::.|||..|         ||..| .:.|:.:...|.||..|.||.:     :...|....
E. coli    67 GVSGEQIVGIGISA---------QGKGLFLLDKNDKPLGNAILSSDRRAMEIVRRWQEDGIPEKL 122

  Fly   126 HSLLK---YVGGQVSLEMEVPKLLWLKRNLSQTFGNIWRVFDLPDFLTWRATGVDTRSLC--SVV 185
            :.|.:   :.|..|||      |.|||.:..:.:..|..|....|:|.|..|||..   |  |.:
E. coli   123 YPLTRQTLWTGHPVSL------LRWLKEHEPERYAQIGCVMMTHDYLRWCLTGVKG---CEESNI 178

  Fly   186 CKWN-YDAANGSWNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGKG-----LTAKAAGELGLS 244
            .:.| |:.:.|.::........:.|:         :...||  .||..     :||:.|...||.
E. coli   179 SESNLYNMSLGEYDPCLTDWLGIAEI---------NHALPP--VVGSAEICGEITAQTAALTGLK 232

  Fly   245 AGTVVSTSLIDAHAGALGMFGCRSKESK-GADDVQGKMALIAGTSTCHMSITRKACFAQGVWGPY 308
            |||.|...|.|..:.||    |...|.: ..:.|.|..|:.:|       |||.  ...|...||
E. coli   233 AGTPVVGGLFDVVSTAL----CAGIEDEFTLNAVMGTWAVTSG-------ITRG--LRDGEAHPY 284

  Fly   309 QDAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELK---SQLGEDKFIYQHLNKLLPELAAARGL 370
                :.|.::|:      |..:.|. .|..|...|:   :|.||..|  ..:|:.:..|..|.|
E. coli   285 ----VYGRYVND------GEFIVHE-ASPTSSGNLEWFTAQWGEISF--DEINQAVASLPKAGG- 335

  Fly   371 SQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTR-HIIE 434
                    |:...|.|:|:.:            ||:||.|          |....|..|| |:::
E. coli   336 --------DLFFLPFLYGSNA------------GLEMTSG----------FYGMQAIHTRAHLLQ 370

  Fly   435 NLYQYG------------RAPF---QTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLVGA 484
            .:|: |            |..|   .||...||.|.:.:::|..||:..|...:|..:|....||
E. coli   371 AIYE-GVVFSHMTHLNRMRERFTDVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGA 434

  Fly   485 AALGAAASGHFDSLESASKSMGGTGQLVKPNAETLEFHNRKYKVFLQLL 533
            |......:|.:.:...|.:.:....:.:.|:....:.:.:||:.:..|:
E. coli   435 ALAARVGTGVYHNFSEAQRDLRHPVRTLLPDMTAHQLYQKKYQRYQHLI 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	138/569 (24%)
lyxK	NP_418037.1	ASKHA_NBD_FGGY_EcLyxK-like	4..443	CDD:466805	132/527 (25%)