DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11594 and Katna1

DIOPT Version :9

Sequence 1:	NP_001261391.1	Gene:	CG11594 / 38473	FlyBaseID:	FBgn0035484	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001004217.2	Gene:	Katna1 / 292464	RGDID:	1303062	Length:	493	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	64/291 - (21%)
Similarity:	106/291 - (36%)	Gaps:	72/291 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSI---CQVVKKVIGGVDKSKVKGI 76
            |:..:|:|...| ||:|..:.:  ::.:..:.:|....:||.|   .:.||:::..::..|:...
  Rat    22 GNYDSAMVYYQG-VLDQINKYL--YSVKDTHLHQKWQQVWQEINVEAKHVKEIMKTLESFKLDST 83

  Fly    77 GFDATCSLVVLGPQGSPLTVSKSGEAEQNIILWM-----------DHRAEQETQEINAFKHSLLK 130
            ...|       .....|   |..||      :|.           ..|..|.||..:...||  .
  Rat    84 SLKA-------AQHELP---SSEGE------VWSLPVPVERRPLPGPRKRQSTQHSDPKPHS--N 130

  Fly   131 YVGGQV--------SLEMEVPKLLWLKRNLSQTFG-----NIWRVFDLPDFLTWRATGVDTRSLC 182
            ..|..|        ||..:..|.:..:....|:.|     .:......|:...:.:||.| :.|.
  Rat   131 RPGAVVRAHRPSAQSLHSDRGKAVRSREKKEQSKGREEKNKLPAAVTEPEANKFDSTGYD-KDLV 194

  Fly   183 SVV----------CKWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSD--------VQPPGRTV 229
            ..:          .:| ||.|:....|:.|::|.:..:....|.| |..        |.|||  .
  Rat   195 EALERDIISQNPNVRW-YDIADLVEAKKLLQEAVVLPMWMPEFFK-GIRRPWKGVLMVGPPG--T 255

  Fly   230 GKGLTAKA-AGELGLSAGTVVSTSLIDAHAG 259
            ||.|.||| |.|...:...|.|::|...:.|
  Rat   256 GKTLLAKAVATECKTTFFNVSSSTLTSKYRG 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_001261391.1	FGGY_YpCarbK_like	5..540	CDD:212663	64/291 (22%)
CG11594	NP_001261391.1	5C_CHO_kinase	6..540	CDD:273552	64/291 (22%)
Katna1	NP_001004217.2	AAA	243..384	CDD:214640	16/46 (35%)
		AAA	247..383	CDD:278434	16/42 (38%)
		Vps4_C	<458..491	CDD:286426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900