Protein Alignment CG11594 and GK5

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001034636.1
• Gene: GK5 / 256356
• HGNCID: 28635
• Length: 529
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 116/574 - (20%)
• Similarity: 202/574 - (35%)
• Gaps: 143/574 - (24%)

  Fly     6 FFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVI--GGV 68
            |.:|:|||:...|..:.....||...:||.::...|:.|:.....|.:|.....|:|:.:  .|:
Human    20 FVLGLDVGSSVIRCHVYDRAARVCGSSVQKVENLYPQIGWVEIDPDVLWIQFVAVIKEAVKAAGI 84

  Fly    69 DKSKVKGIGFDATCSLVVLGPQGSPLTVSKSGEAEQNIILWMDHRAEQETQEIN----------- 122
            ..:::.|:|.....:..:...:       |:|....|.|.|.|.||.:..:..|
Human    85 QMNQIVGLGISTQRATFITWNK-------KTGNHFHNFISWQDLRAVELVKSWNNSLLMKIFHSS 142

  Fly   123 ------------AFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQT----------FGNI--WRVF 163
                        .|..||..:...|.||     :|:|:.:||::.          ||.|  |.::
Human   143 CRVLHFFTRSKRLFTASLFTFTTQQTSL-----RLVWILQNLTEVQKAVEEENCCFGTIDTWLLY 202

  Fly   164 DL-------PDFLTWRATGV-DTRSLCSVVCKWNYDAANGSWNKEF--LKQADLEEL-----TQN 213
            .|       .||.....||: |...:|              |:...  |....|..|     |.:
Human   203 KLTKGSVYATDFSNASTTGLFDPYKMC--------------WSGMITSLISIPLSLLPPVRDTSH 253

  Fly   214 NFEKLGSDVQPPGRTVGKGLTAKAAGELGLSAGTVVSTSLIDAHAGALGMFG-CRSKESKGADDV 277
            ||..:..::                  .|:....|   :|:.....|  ||| |..:
Human   254 NFGSVDEEI------------------FGVPIPIV---ALVADQQSA--MFGECCFQ-------- 287

  Fly   278 QGKMALIAGTSTCHMSITRKACFAQGVWGPYQDAIIPGYFLNEG----GQSIAGHLLDHVLKSHE 338
            .|.:.|..||.| .:.|.......|...|.|.   :.|:.:.:.    .:|.||          :
Human   288 TGDVKLTMGTGT-FLDINTGNSLQQTTGGFYP---LIGWKIGQEVVCLAESNAG----------D 338

  Fly   339 SYAELKSQLGEDKFI-YQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVI 402
            :...:|.....|.|. .....|:...|..:.|:..|          |...|.::|:.||......
Human   339 TGTAIKWAQQLDLFTDAAETEKMAKSLEDSEGVCFV----------PSFSGLQAPLNDPWACASF 393

  Fly   403 TGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADIC 467
            .||..:.....|.   .|.::::|:..:.:.|.:.:....|.:.:...||:.||...:|..:|:.
Human   394 MGLKPSTSKYHLV---RAILESIAFRNKQLYEMMKKEIHIPVRKIRADGGVCKNGFVMQMTSDLI 455

  Fly   468 NLPALIPDEQEMVLVGAAALGAAASGHFDSLESASKSMGGTGQLVKPNAETLEF 521
            |.....|.:.:|..:|||:|...|.|.:...|.. |.:..:..:.||..:..|:
Human   456 NENIDRPADIDMSCLGAASLAGLAVGFWTDKEEL-KKLRQSEVVFKPQKKCQEY 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	116/574 (20%)
GK5	NP_001034636.1	ASKHA_NBD_FGGY_GK5-like	20..520	CDD:466803	116/574 (20%)