DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11594 and Katna1

DIOPT Version :10

Sequence 1:NP_647848.2 Gene:CG11594 / 38473 FlyBaseID:FBgn0035484 Length:548 Species:Drosophila melanogaster
Sequence 2:NP_035965.3 Gene:Katna1 / 23924 MGIID:1344353 Length:491 Species:Mus musculus


Alignment Length:82 Identity:26/82 - (31%)
Similarity:37/82 - (45%) Gaps:13/82 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   187 KWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSD--------VQPPGRTVGKGLTAKA-AGELG 242
            :| ||.|:....|:.|::|.:..:....|.| |..        |.|||  .||.|.||| |.|..
Mouse   207 RW-YDIADLVEAKKLLQEAVVLPMWMPEFFK-GIRRPWKGVLMVGPPG--TGKTLLAKAVATECK 267

  Fly   243 LSAGTVVSTSLIDAHAG 259
            .:...|.|::|...:.|
Mouse   268 TTFFNVSSSTLTSKYRG 284

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11594NP_647848.2 5C_CHO_kinase 6..540 CDD:273552 26/82 (32%)
Katna1NP_035965.3 Interaction with microtubules, sufficient for microtubule severing activity. /evidence=ECO:0000269|PubMed:28436967 1..185
Interaction with dynein and NDEL1. /evidence=ECO:0000250 1..75
Interaction with KATNB1 1..29
Kp60-NTD 4..72 CDD:439297
SpoVK 61..469 CDD:440232 26/82 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 101..182
RecA-like_KTNA1 210..379 CDD:410930 24/78 (31%)
Vps4_C <456..489 CDD:462762
Blue background indicates that the domain is not in the aligned region.

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