Protein Alignment CG11594 and Gk5

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001355808.1
• Gene: Gk5 / 235533
• MGIID: 2443336
• Length: 534
• Species: Mus musculus
• Alignment Length: 579
• Identity: 114/579 - (19%)
• Similarity: 199/579 - (34%)
• Gaps: 142/579 - (24%)

  Fly     2 SSGP---FFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKK 63
            |:.|   |.:|:|||:...|..:.....||...:.|.::...|:||:.....|::|.....|:|.
Mouse    18 SASPPSRFVLGLDVGSTVIRCHVYDQTARVRGSSAQKVENVYPQPGWVEIDPDSLWAQFVAVIKD 82

  Fly    64 VI--GGVDKSKVKGIGFDATCSLVVLGPQGSPLTVSKSGEAEQNIILWMDHRAEQ---------- 116
            .:  .||..:::.|:|.....:..:...:       |:|....|.|.|.|.||.:
Mouse    83 AVKAAGVQMNQIVGLGISTQRATFITWNK-------KTGHHFHNFISWQDLRAAELVKSWNNSLI 140

  Fly   117 ------ETQEINAFKHS--LLKYVGGQVSLEMEVPKLLWLKRNLSQT----------FGNI--WR 161
                  .|:.::.|..|  :|.......|.:....:|.|:.:|||:.          ||.|  |.
Mouse   141 MKLLHGATRVLHFFSRSKVMLTVSRFNFSTQHATLRLTWILQNLSEVKRAVEEDNCCFGTIDTWL 205

  Fly   162 VFDL-------PDFLTWRATGVDTRSLCSVVCKWNYDAANGSWNKEFLKQADLE-------ELTQ 212
            ::.|       .|:.....||.             :|.....|::.......:.       :.|.
Mouse   206 LYKLTKGSSYATDYSNASTTGF-------------FDPYAMRWSRLITTMVSIPLSILPPVKDTS 257

  Fly   213 NNF----EKLGSDVQPPGRTVGKGLTAK------AAGELGLSAGTVVSTSLIDAHAGALGMFGCR 267
            .||    ||:.....|....||...:|.      ..|::.|:.||   .:.:|.:.|
Mouse   258 YNFGSVDEKIFGVPIPVVALVGDQQSAMFGECCFETGDVKLTMGT---GTFLDINTG-------- 311

  Fly   268 SKESKGADDVQGKMALIAGTSTCHMSITRKACFAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLDH 332
                |....|.|....:.|.......:    |.|:|..|....||:
Mouse   312 ----KNLQHVNGGFYPLIGWKIGQELV----CLAEGNAGDTGTAIM------------------- 349

  Fly   333 VLKSHESYAELKSQLGEDKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPT 397
                   :|: |..|..|.   ....|:...|..:.|          |:..|...|.::|:.||.
Mouse   350 -------WAQ-KLDLFTDA---AETEKMALSLEDSEG----------VYFVPSFSGLQAPLNDPC 393

  Fly   398 LRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQC 462
            ......||..:.....|.   .|.::::|:..:.:.:.|.:..:.|...:...||:..|...:|.
Mouse   394 ACASFMGLKHSTNKYHLV---RAILESIAFRNKQLYDMLQREIQIPVTNIRADGGVCNNAFVMQM 455

  Fly   463 HADICNLPALIPDEQEMVLVGAAALGAAASGHFDSLESASKSMGGTGQLVKPNAETLEF 521
            .:|:.|.....|...:|..:|||:|...|.|.:...|...| :..:..:.||..:..|:
Mouse   456 TSDLINEKIDRPAHFDMSCLGAASLAGLAVGFWADKEELQK-LRQSEMVFKPQKKWQEY 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	112/572 (20%)
Gk5	NP_001355808.1	ASKHA_NBD_FGGY_GK5-like	25..525	CDD:466803	112/572 (20%)