DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11594 and shpk

DIOPT Version :9

Sequence 1:	NP_001261391.1	Gene:	CG11594 / 38473	FlyBaseID:	FBgn0035484	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_001341627.4	Gene:	shpk / 100001676	ZFINID:	ZDB-GENE-060526-357	Length:	469	Species:	Danio rerio

Alignment Length:	536	Identity:	108/536 - (20%)
Similarity:	169/536 - (31%)	Gaps:	163/536 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVIGGVDK 70
            |.:|:|:||.|.:..|:....:.:.::.......:.....:..:.:.....|...:.:.:..:.|
Zfish    11 FVLGMDLGTTSVKVVLLEAQSKTVTESRSFTTNADISSSTHTHAKEQDPALIIAALDQCMAALPK 75

  Fly    71 SKVKGIGFDATCSLVVLGPQGSPLTVSKSGEAEQN--------------IILWMDHRAEQETQEI 121
            .|:|.:.|...|..:    .|..|..|.||...|:              :|.|.|.|.:.:....
Zfish    76 DKLKKVKFIGVCGQM----HGIVLWKSNSGCEWQSKDGITRFSPKDVSQLITWQDGRCDFDFLSA 136

  Fly   122 NAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTFG---NIWRVFDLPDFLT-WRATGVDTRSLC 182
            .....|.|....|                     ||   ..|.:...|:||: :...|.....:.
Zfish   137 LPKPDSHLSVATG---------------------FGCATVFWYMKHRPEFLSGFSDAGTIQDYVV 180

  Fly   183 SVVC-------------KWNY-DAANGSWNKEFLKQAD-----LEELTQNNFEKLGSDVQPPGRT 228
            |::|             .|.| :.|...||...||.|.     |..|..:            ||.
Zfish   181 SMLCSLDKCVMTGQNAASWGYFNTATNQWNTHILKDAGFPVHLLPVLVDS------------GRV 233

  Fly   229 VGKGLTAKAAGELGLSAGTVVSTSLIDAHAGALGMFGCRSKESKGADDVQGKMALIAGTSTCHMS 293
            .|.    .:....|:.|.|.|        ..|||.|.| |..|...|         .|.:..:||
Zfish   234 AGH----TSCEWYGIPAHTAV--------GAALGDFQC-SVYSCITD---------RGHAVLNMS 276

  Fly   294 ITRKACF---AQGVWGPYQDAIIP-GYF-------------LNEGGQSIAG--HLLDHVLKSHES 339
            .:.:..|   |:.......|.:.| .||             || ||..:|.  .:||..:|
Zfish   277 TSAQLTFRMPAEFTPTSSPDPLSPIAYFPYFEGSYLAVAASLN-GGNVMATFVRMLDSWMK---- 336

  Fly   340 YAELKSQLGEDKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITG 404
              |...::.|.....|.::..|.:            ...|:.|...|.|.|...:.......|:.
Zfish   337 --EFGLEVSESSIYSQLIHSALAQ------------PNTDLTVTSTLLGERHAPSSSASVSHISS 387

  Fly   405 LDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQC-----HA 464
            .:::.|..:.|:            .|.|||||..  ..|.|:|...|        |:|     .|
Zfish   388 SNLSLGHVTRAV------------CRGIIENLAT--MMPPQSLRAAG--------VRCIIGSGSA 430

  Fly   465 DICNLPALIPDEQEMV 480
            ..||  |::..|.|.|
Zfish   431 LSCN--AVLQQEVERV 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_001261391.1	FGGY_YpCarbK_like	5..540	CDD:212663	108/536 (20%)
CG11594	NP_001261391.1	5C_CHO_kinase	6..540	CDD:273552	108/536 (20%)
shpk	XP_001341627.4	FGGY_SHK_like	11..464	CDD:212661	108/536 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810