Protein Alignment Mul1 and MUL1

DIOPT Version :9

• Sequence 1: NP_001303365.1
• Gene: Mul1 / 38472
• FlyBaseID: FBgn0035483
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_078820.2
• Gene: MUL1 / 79594
• HGNCID: 25762
• Length: 352
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 106/336 - (31%)
• Similarity: 180/336 - (53%)
• Gaps: 26/336 - (7%)

  Fly    15 LILG----LCAREYVHYKRTAKV---LKAAPQYNIDGDLKSVVERQRDKKIPYAVIRGTVTPIGV 72
            ::||    :.|..|..|::.|:|   ||.|.:.::..||||::.....|.:|||||.|.|..:..
Human    13 ILLGTTSVVTAALYSVYRQKARVSQELKGAKKVHLGEDLKSILSEAPGKCVPYAVIEGAVRSVKE 77

  Fly    73 PLRSSLVPSVSGVLQIVKLHEHR-VTRGFAGFWTEQHKLLHESANEMPFELRNQSHGVE----IV 132
            .|.|..|.:..||:|.:.|.||: |.......|.:..|::|:..|.:||:|.....||:    ::
Human    78 TLNSQFVENCKGVIQRLTLQEHKMVWNRTTHLWNDCSKIIHQRTNTVPFDLVPHEDGVDVAVRVL 142

  Fly   133 DALSAAVLDVDVVYDNYEPSNLSLFDHVFGFFSGVRQRGLQTTEEVLREGSFLTAIGELELDGDT 197
            ..|.:..|.::.||:.:.||..|..|.:..:.||.|.:|:|.|||:|:.|:.||.:|||.||.::
Human   143 KPLDSVDLGLETVYEKFHPSIQSFTDVIGHYISGERPKGIQETEEMLKVGATLTGVGELVLDNNS 207

  Fly   198 LRMQPSNEG-PLFLTTATKSTLIKRFEDA-KTTTILKLV----VCSTISAILVAFIAKKLYRKRK 256
            :|:||..:| ..:|::....:|::|.|.: :...:|.||    .|:|:     .||.:|.|.:|:
Human   208 VRLQPPKQGMQYYLSSQDFDSLLQRQESSVRLWKVLALVFGFATCATL-----FFILRKQYLQRQ 267

  Fly   257 QEREEAKIRERLDTERRERRARSRPHTL-SQDQLCVVCSTNPKEIILLPCGHVCLCEDCAQKI-- 318
            :.....:::|.......:..:|::|... |....||||.::.|..:.|.|||||.|.:|.:.:
Human   268 ERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSFKSCVFLECGHVCSCTECYRALPE 332

  Fly   319 SVTCPVCRGSI 329
            ...||:||.:|
Human   333 PKKCPICRQAI 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mul1	NP_001303365.1	GIDE	89..243	CDD:315205	51/164 (31%)
		zf-C3HC4_3	286..329	CDD:316442	17/44 (39%)
		modified RING-HC finger (C3HC5-type)	290..325	CDD:319701	15/36 (42%)
MUL1	NP_078820.2	GIDE	97..253	CDD:372140	48/155 (31%)
		PEX10	<260..341	CDD:227861	23/80 (29%)
		mRING-HC-C3HC5_MAPL	301..340	CDD:319562	15/38 (39%)
		modified RING-HC finger (C3HC5-type)	302..339	CDD:319562	15/36 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159039
Domainoid	1	1.000	82	1.000	Domainoid score	I8464
eggNOG	1	0.900	-	-		E1_KOG1571
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4131
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60264
OrthoDB	1	1.010	-	-		D582825at33208
OrthoFinder	1	1.000	-	-		FOG0003714
OrthoInspector	1	1.000	-	-		oto89178
orthoMCL	1	0.900	-	-		OOG6_105337
Panther	1	1.100	-	-	O	PTHR12183
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5756
SonicParanoid	1	1.000	-	-		X4137
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800