DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mul1 and Mul1

DIOPT Version :9

Sequence 1:	NP_001303365.1	Gene:	Mul1 / 38472	FlyBaseID:	FBgn0035483	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	XP_036020280.1	Gene:	Mul1 / 68350	MGIID:	1915600	Length:	378	Species:	Mus musculus

Alignment Length:	309	Identity:	99/309 - (32%)
Similarity:	158/309 - (51%)	Gaps:	19/309 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 KAAPQYNIDGDLKSVVERQRDKKIPYAVIRGTVTPIGVPLRSSLVPSVSGVLQIVKLHEHR-VTR 98
            :.|.:.::..|||.::.....|.:|||||.|.|..:...|.|..|.:..||:|.:.|.||: |..
Mouse    66 QGAKKIHLGEDLKGILSEAPGKCVPYAVIEGAVRSVKETLNSQFVENCKGVIQRLSLQEHKMVWN 130

  Fly    99 GFAGFWTEQHKLLHESANEMPFELRNQSHG----VEIVDALSAAVLDVDVVYDNYEPSNLSLFDH 159
            .....|.:..|::|:..|.:||:|.....|    |.::..|.:..|.::.||:.:.||..|..|.
Mouse   131 RTTHLWNDYSKIIHQRTNTVPFDLVPHEDGVAVSVRVLKPLDSVDLGLETVYEKFHPSVQSFTDA 195

  Fly   160 VFGFFSGVRQRGLQTTEEVLREGSFLTAIGELELDGDTLRMQPSNEG-PLFLTTATKSTLIKRFE 223
            :..:.||.|.:|:|.|||:|:.|:.||.||||.||.:.:|:||..:| ..:|::....:|:.|.|
Mouse   196 IGHYISGERPKGIQETEEMLKVGATLTGIGELVLDNNAVRLQPPKQGMQYYLSSQDFDSLLHRQE 260

  Fly   224 DA-KTTTILKLV----VCSTISAILVAFIAKKLYRKRKQEREEAKIRERLDTERRERRARSRPHT 283
            .: :...||.||    .|:|:     .||.:|.|..|::...:.:::|.......:..:::.|..
Mouse   261 SSVRLWKILVLVFGFATCATL-----FFILRKQYLHRQERLRQQQLQEEFLEHEAQLLSQASPED 320

  Fly   284 L-SQDQLCVVCSTNPKEIILLPCGHVCLCEDC--AQKISVTCPVCRGSI 329
            . |....||||.:|.|..:.|.|||||.|..|  |......||:||..|
Mouse   321 RESLKSACVVCLSNFKSCVFLECGHVCSCRQCYLALPEPKRCPICRREI 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mul1	NP_001303365.1	GIDE	89..243	CDD:315205	53/164 (32%)
		zf-C3HC4_3	286..329	CDD:316442	19/44 (43%)
		modified RING-HC finger (C3HC5-type)	290..325	CDD:319701	17/36 (47%)
Mul1	XP_036020280.1	GIDE	123..279	CDD:403620	53/166 (32%)
Mul1	XP_036020280.1	mRING-HC-C3HC5_MAPL	327..366	CDD:319562	16/36 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849415
Domainoid	1	1.000	82	1.000	Domainoid score	I8451
eggNOG	1	0.900	-	-		E1_KOG1571
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4151
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60264
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003714
OrthoInspector	1	1.000	-	-		oto92742
orthoMCL	1	0.900	-	-		OOG6_105337
Panther	1	1.100	-	-	O	PTHR12183
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5756
SonicParanoid	1	1.000	-	-		X4137
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790