Protein Alignment Mul1 and exc-14

DIOPT Version :10

• Sequence 1: NP_647847.1
• Gene: Mul1 / 38472
• FlyBaseID: FBgn0035483
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_504354.1
• Gene: exc-14 / 178892
• WormBaseID: WBGene00019649
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 318
• Identity: 75/318 - (23%)
• Similarity: 123/318 - (38%)
• Gaps: 71/318 - (22%)

  Fly    51 ERQRDKK---IPYAVIRGTVTPIGVPLRSSLVPSVSGVLQIVKLHEHRVTRGFAGFWTEQHKLLH 112
            |::||:|   ..:.:::..:.    .|.:.....:|.|.::.:|.|.          :||.  |.
 Worm   123 EKERDRKEVDSQFTILKNRIN----HLENEKEQCLSEVQELKRLLED----------SEQD--LK 171

  Fly   113 ESANEMPFELRNQSHGVEIVDALSAAVL----DVDVVYDNYEPSNLSLFDHVFGFFSGVRQRGLQ 173
            :..:||.   |.....||..|||....:    ....::|..|     |.:|....:|..:.|
 Worm   172 DCKDEMN---RLMEERVETADALDKLTIQNYRQQQEIHDQKE-----LSEHRKKIYSEEKAR--- 225

  Fly   174 TTEEVLREGSFLTAIG-ELELDGDTLRMQPSNEGPLFLTTATKSTLIKRFE-------DAKTTTI 230
            ..||:|......|.:. |||...:.|..|         |..||....|.::       |..|...
 Worm   226 KDEEILNLQKQKTDVEMELERKSNLLDEQ---------TNVTKRMEEKSYQLKPLVLLDELTKKH 281

  Fly   231 LKLVVCST-----ISAILVAFIAKKLYRKRKQEREEAKIRE-RLDTERR------ERRARSRPHT 283
            .:||..||     |:|:.:.:  |:|:....|  .|..:.| :|..|||      :.|:|:|...
 Worm   282 SQLVDLSTEFLPNINAVKMLY--KELFESFPQ--LETNVHESKLSMERRVEEVEEQLRSRNRDFQ 342

  Fly   284 LSQDQL---CVVCSTNPKEIILLPCGHVCLCEDCAQKISV-TCPVCRGSIVSKAAAFI 337
            ..|::|   |.:|......|:.:||.|:..|..|...... .||.||.:|.:....|:
 Worm   343 RLQEKLVAECCICLATKPSIVFMPCRHLITCSGCYDASDFRECPTCRSTIENSITVFM 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mul1	NP_647847.1	GIDE	89..243	CDD:403620	40/170 (24%)
		mRING-HC-C3HC5_CGRF1-like	288..326	CDD:438311	11/41 (27%)
exc-14	NP_504354.1	Smc	<114..>264	CDD:440809	38/176 (22%)
		RING-HC_MIP1-like	347..398	CDD:438490	14/50 (28%)