DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxL1 and Foxl1

DIOPT Version :9

Sequence 1:	NP_001246609.1	Gene:	FoxL1 / 38471	FlyBaseID:	FBgn0004895	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	XP_006255788.1	Gene:	Foxl1 / 687553	RGDID:	1584212	Length:	341	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	120/308 - (38%)
Similarity:	153/308 - (49%)	Gaps:	82/308 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 GLPISF-----LHNSHR---PEKPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQ 133
            |||::|     |....|   |:|||:||||||||||..||.||:||:|||:||||:||:|.:|:|
  Rat    27 GLPLAFAPATALAGPGRVEPPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQ 91

  Fly   134 GWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRHCG 198
            |||||||||||||:||||:||:|.      ..||||||.||....||||.||||||:.:.:...|
  Rat    92 GWQNSIRHNLSLNECFVKVPREKG------RPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPAAG 150

  Fly   199 HP----NRYE-RESGKDSNDGNSSAAEIRSPSEPLSDFDIFCNERPNYSDRITDLHRQYLSVSLG 258
            .|    .|.| |||....:.|:.:.|..|...||               ||..       |.:.|
  Rat   151 SPEAKRTRVEPRESEVGCDVGSPNLATARPMHEP---------------DRSQ-------SPAAG 193

  Fly   259 FNSLFNNEARGLR---PLPEIRECPDDVDASSSSSKAMQSSMELHEELHSPSAFTPPLNRRETSS 320
                  ..||...   |.||:|:  .|.|.:...:.|:.|. :|...:|.|.        ....|
  Rat   194 ------GTARSALLPWPGPELRD--PDADRTIQDAGAVASG-QLERPVHYPV--------HHLGS 241

  Fly   321 SGAPVLAEAFNGIKDVVDAPGSSPVASSNRSKTTLFTIDNIIG---KP 365
            |..|              ||..||..|.::|    |:||:|:.   ||
  Rat   242 SLRP--------------APSGSPKGSKSKS----FSIDSILAVRPKP 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	63/93 (68%)
Foxl1	XP_006255788.1	FH	49..137	CDD:214627	63/93 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349607
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2284
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850