Protein Alignment FoxL1 and FOXL2

DIOPT Version :9

• Sequence 1: NP_001246609.1
• Gene: FoxL1 / 38471
• FlyBaseID: FBgn0004895
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_075555.1
• Gene: FOXL2 / 668
• HGNCID: 1092
• Length: 376
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 105/349 - (30%)
• Similarity: 156/349 - (44%)
• Gaps: 83/349 - (23%)

  Fly    13 PDNEELVNSMLANPDYLRTQVSPN--PLAPSAVGGAGMEGLMCGSFSPAFYYQGIDSFLALHNNI 75
            |:.|:...::|| |:..||...|.  |.:|...||.|      |..:|
Human     6 PEPEDAAGALLA-PETGRTVKEPEGPPPSPGKGGGGG------GGTAP----------------- 46

  Fly    76 WGLPISFLHNSHRP---EKPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQN 137
                       .:|   :|||:||:|||||||..:..:||||||||::|:.|||:|.:||:||||
Human    47 -----------EKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQN 100

  Fly   138 SIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRHCGHPNR 202
            |||||||||:||:|:||      :.....||:||.||.:..||||:|||||||..::.....|..
Human   101 SIRHNLSLNECFIKVPR------EGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAH 159

  Fly   203 YERESGKDSNDGNSSAAEIRSPSEPLSDFDIFCNERPNYSDRITDLHRQYLSVSLGFNSLFNNEA 267
            ::...|.....|.:....:....            ...|.         ||:......|.|.|.:
Human   160 FQPGKGLFGAGGAAGGCGVAGAG------------ADGYG---------YLAPPKYLQSGFLNNS 203

  Fly   268 RGLRPLPE------IRECPDDVDASSSSSKAMQS------SMELHEELHSPSAFTPPLNRRETSS 320
               .|||:      ...|.....|:::::.|..:      :..:.:.|..|:|...|..|.: |.
Human   204 ---WPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQ-SM 264

  Fly   321 SGAPVLAEAFNGIKDVVDAPGSSP 344
            :..|.:..::||:.....||...|
Human   265 ALPPGVVNSYNGLGGPPAAPPPPP 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	55/93 (59%)
FOXL2	NP_075555.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		16/81 (20%)
		Forkhead	53..139	CDD:365978	53/91 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..342		4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920