DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxL1 and Foxj2

DIOPT Version :9

Sequence 1:	NP_001246609.1	Gene:	FoxL1 / 38471	FlyBaseID:	FBgn0004895	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_068699.1	Gene:	Foxj2 / 60611	MGIID:	1926805	Length:	565	Species:	Mus musculus

Alignment Length:	301	Identity:	89/301 - (29%)
Similarity:	126/301 - (41%)	Gaps:	72/301 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 HRPEKPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVK 151
            |:..||.:||..||..||:|:|.:::|||.||::|.|.||||:....||:||||||||||.||.|
Mouse    62 HQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRK 126

  Fly   152 IPRDKNTIEDNDSAGKGSYWMLDS----------SASDMFEQGNYRRRRTRRQR----------- 195
            :||.:      |..||||||.:|:          ...|...|.:..:..::..|
Mouse   127 VPRPR------DDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVPGSGEASL 185

  Fly   196 -HCGHPN----------RYERESGKDSNDGNSSAA-----EIRSPSEPL----SDFDIFCNERPN 240
             |.|.|.          .|.:  |..|.||.:.||     |....:.||    .||. |.....|
Mouse   186 SHEGTPQMSLQSPSSVANYSQ--GPGSVDGGAVAAGAPGQESTEGAPPLYNTNHDFK-FSYSEIN 247

  Fly   241 YSD---RITDLHRQYL----SVSLGFNSLF------NN-----EARGLRPLPEIRECPDDVDASS 287
            :.|   ...:|::..|    |...||:||.      ||     :.:..:|.|:.:..|.......
Mouse   248 FQDLSWSFRNLYKSMLERSSSSQHGFSSLLGDMPPSNNYYVYQQQQQQQPPPQPQPPPQQPQPQQ 312

  Fly   288 SSSKAM-QSSMELHEELHSPS---AFTPPLNRRETSSSGAP 324
            ..:... .|::.....||:||   ..||...:......|.|
Mouse   313 QQAPTQGPSNVGGAPPLHTPSPDGCTTPGGKQAGAEGYGPP 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	48/103 (47%)
Foxj2	NP_068699.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..61
		Forkhead	66..143	CDD:278670	45/82 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	125..233		26/115 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..399		12/64 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	543..565
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820