DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxL1 and foxd1

DIOPT Version :9

Sequence 1:	NP_001246609.1	Gene:	FoxL1 / 38471	FlyBaseID:	FBgn0004895	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001008148.1	Gene:	foxd1 / 493510	XenbaseID:	XB-GENE-488077	Length:	329	Species:	Xenopus tropicalis

Alignment Length:	268	Identity:	91/268 - (33%)
Similarity:	131/268 - (48%)	Gaps:	51/268 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 KPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRD 155
            |||:||||||.|||..:|.:|||||.|.:||.::||||||....||||||||||||||||||||:
Frog    68 KPPYSYIALITMAILQSPKKRLTLSEICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPRE 132

  Fly   156 KNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRHCGHPNRYERESGKDSNDGNSSAAE 220
            ..      :.|||:||.||..::|||:.|::.|||.|.:|... |....||.|.
Frog   133 PG------NPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQQA-PELVLREPGH----------- 179

  Fly   221 IRSPSEPLSDFDIFCNERPNYSDRITDLHRQYLSVSLGFNSLFNNEARGLRPLPEIRECPDDVDA 285
             ..|:...|.....|    .|..::...|..  |..:.|.          :...:.|:.|..:..
Frog   180 -FLPASAYSYGPYSC----AYGIQLQPFHPH--SALIAFQ----------QQQQQARQQPPSLPP 227

  Fly   286 SSSSSKAMQSSMEL------HEELHSPSAFTPPLNRRETSSSGAPVLAEAFNGIKDVVDA---PG 341
            .::.:....::.:|      :....||:|..|.|..:.:|:     ||.:...|:.::..   ||
Frog   228 MAAPALMPPAAQDLSRTCTFYPHQLSPAALPPSLQSKSSSA-----LARSTFSIESIIGGDLNPG 287

  Fly   342 --SSPVAS 347
              :||.|:
Frog   288 QCNSPKAA 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	57/93 (61%)
foxd1	NP_001008148.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..63
foxd1	NP_001008148.1	Forkhead	68..153	CDD:365978	56/90 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920