DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxL1 and foxj1.2

DIOPT Version :9

Sequence 1:	NP_001246609.1	Gene:	FoxL1 / 38471	FlyBaseID:	FBgn0004895	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001008143.1	Gene:	foxj1.2 / 493505	XenbaseID:	XB-GENE-919738	Length:	371	Species:	Xenopus tropicalis

Alignment Length:	293	Identity:	85/293 - (29%)
Similarity:	123/293 - (41%)	Gaps:	89/293 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 KPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRD 155
            |||:||..||.||:.::..::||||.||.:|...|.|||.....||||||||||||.||:|:||.
Frog   109 KPPYSYATLICMAMEASQQRKLTLSAIYSWITQNFCYYRHADPSWQNSIRHNLSLNKCFMKVPRG 173

  Fly   156 KNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRR---------------------------TRR 193
            |      |..|||.:|.:|...:|||..|..:|||                           :..
Frog   174 K------DEPGKGGFWQMDPRYADMFVNGVLKRRRMPASHLDPPRCNKAIAHHPYLPVSRPSSHH 232

  Fly   194 QRHC--GH--PNRYERESGKDSNDGNSSAAEIRSPSEPLSDFDIFCNERPNYSDRITDLHRQYLS 254
            .:|.  ||  ..|||:.        |.....:|:| |...| .:|..|.|.......||..|...
Frog   233 MQHISGGHRQSRRYEKP--------NPVLPALRAP-ERQGD-ALFTPEDPLQGSNFDDLDLQTAL 287

  Fly   255 VSLGFNSLFNNEARGLRPLPEIRECPDDVDASS-SSSKAMQSSMELHEELHSPSAFTPPL--NRR 316
            :|:.:..                    |:.||: :|:....|.|:::.:       .||:  |..
Frog   288 ISMCWEG--------------------DLAASNLNSTLTGTSGMDMNLQ-------DPPMQDNHW 325

  Fly   317 ETSSSG---------APVLAEAFNG---IKDVV 337
            ..|:.|         .||:.:.:|.   ::||:
Frog   326 YLSTEGQQTWEQVKEEPVVEQWYNETGFVEDVL 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	47/93 (51%)
foxj1.2	NP_001008143.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..74
		COG5025	<61..>262	CDD:227358	61/167 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..99
		Forkhead	108..194	CDD:365978	46/90 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	228..248		5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940