Protein Alignment FoxL1 and FOXI2

DIOPT Version :9

• Sequence 1: NP_001246609.1
• Gene: FoxL1 / 38471
• FlyBaseID: FBgn0004895
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_997309.2
• Gene: FOXI2 / 399823
• HGNCID: 32448
• Length: 318
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 95/276 - (34%)
• Similarity: 129/276 - (46%)
• Gaps: 50/276 - (18%)

  Fly    24 ANPDYLRTQVSPNPLAP---SAVGGAGMEGLMCGSFSPAFY--------------YQGIDSFLAL 71
            |.|...:....|....|   .||||..:..:...:.||..|              |......|..
Human    13 APPGQAQATAHPPGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPYAAPSYGAPGPLLGA 77

  Fly    72 HNNIWGLPISFLHNSHRPE-----KPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYREN 131
            ...:.|..:::|..|.:.|     :||:||.|||||||.|||.::||||.||:::...||:|:.:
Human    78 PGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRS 142

  Fly   132 KQGWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRH 196
            |.||||||||||||||||.|:|||:      |..|||:||.||.:...||:.||:||:|.||
Human   143 KAGWQNSIRHNLSLNDCFKKVPRDE------DDPGKGNYWTLDPNCEKMFDNGNFRRKRKRR--- 198

  Fly   197 CGHPNRYERESGKDSNDGNSSAAEIRSPS-EPLSD--FDIFCNERPNYSDRITDLHRQYLSVSLG 258
                    .|:......|..|.....:|: ||.|.  .|:..:..|:..:..|...        |
Human   199 --------AEASAAVRSGARSVGGAEAPALEPPSAACLDLQASPSPSAPEAATCFS--------G 247

  Fly   259 FNSLFNNEARGLRPLP 274
            |.|..:..|.||...|
Human   248 FASAMSALAGGLGTFP 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	54/93 (58%)
FOXI2	NP_997309.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		3/16 (19%)
		Forkhead	102..188	CDD:278670	54/91 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920