Protein Alignment FoxL1 and foxa3

DIOPT Version :10

• Sequence 1: NP_523912.1
• Gene: FoxL1 / 38471
• FlyBaseID: FBgn0004895
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_571374.1
• Gene: foxa3 / 30559
• ZFINID: ZDB-GENE-980526-423
• Length: 441
• Species: Danio rerio
• Alignment Length: 386
• Identity: 119/386 - (30%)
• Similarity: 164/386 - (42%)
• Gaps: 86/386 - (22%)

  Fly     3 PSCYANGSMLPDNEELVNSMLANPDYLRTQVSPNPLAPSAVGGAGMEGLMCGSFSPAFYYQGIDS 67
            ||...|.|.|       :||...|:::......:.|.||::...|......|   |..:||.:..
Zfish    58 PSAGLNSSPL-------SSMGGGPNHMSLSPVGSSLNPSSLTQLGSSASTLG---PLSHYQSMGQ 112

  Fly    68 FLALHNNIWGLPISFLHNSHRPE---------KPPFSYIALIAMAISSAPNQRLTLSGIYKFIMD 123
              .:....:..|.|.......|:         |||:|||:||.|||..:.::.|||:.||::|||
Zfish   113 --PMSQISYPSPTSLNRTKEMPKPYRRSLTHAKPPYSYISLITMAIQQSQSKMLTLNEIYQWIMD 175

  Fly   124 KFPYYRENKQGWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRR 188
            .|||||||:|.|||||||:||.||||||:.|..      |..||||||.|..::.:|||.|.|.|
Zfish   176 LFPYYRENQQRWQNSIRHSLSFNDCFVKVARSP------DKPGKGSYWALHPNSGNMFENGCYLR 234

  Fly   189 RRTRRQRHCGHPNRYERESGKDSN----DGNSSAA--------EIRSPSEPLSDFDIFCNERPNY 241
            |:.|        .:.|.::||.|:    ||:|:..        |..||:              ..
Zfish   235 RQKR--------FKIEEKAGKKSSSKSQDGSSTKGTHSSEGMQEEHSPT--------------TG 277

  Fly   242 SDRITDLHRQYLSVSLGFNSLFNNEARGLRPLPEIRECPDD---------VDASSSSSKAM-QSS 296
            ||.....|    |.|....|....:.|.|..|    :||..         |...||.|.:| .||
Zfish   278 SDGAESAH----SDSSHAGSTSEEQQRSLVQL----DCPSQAPNLLHSSPVPIPSSVSASMPPSS 334

  Fly   297 MELHEE--LHSPSAFTPPLNRRETSSSGAPVLAEAFNGIKDVVDAPGSSPVASSNRSKTTL 355
            ..||.:  .:||.....|::..:..:.....:...||     .:.|.|.....||..|..|
Zfish   335 SHLHSQGMGNSPHLLGSPMHHLDLQNDPLKSMDPHFN-----FNHPFSITNLMSNEQKMDL 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_523912.1	FH_FOX	89..186	CDD:469596	56/105 (53%)
foxa3	NP_571374.1	Forkhead_N	17..142	CDD:369872	19/95 (20%)
		FH_FOXA3	141..242	CDD:410814	59/114 (52%)
		HNF_C	373..>408	CDD:430552	6/18 (33%)