Protein Alignment FoxL1 and foxo3b

DIOPT Version :10

• Sequence 1: NP_523912.1
• Gene: FoxL1 / 38471
• FlyBaseID: FBgn0004895
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_571160.1
• Gene: foxo3b / 30296
• ZFINID: ZDB-GENE-990708-6
• Length: 651
• Species: Danio rerio
• Alignment Length: 348
• Identity: 92/348 - (26%)
• Similarity: 137/348 - (39%)
• Gaps: 123/348 - (35%)

  Fly    74 NIWGLPISFLHNSHRPEKPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRE-----NKQ 133
            |.||               ..||..||..||.|.|::|||||.||.:::...||:::     :..
Zfish   125 NAWG---------------NLSYADLITKAIESTPDKRLTLSQIYDWMVSSVPYFKDKGDSNSSA 174

  Fly   134 GWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRHCG 198
            ||:|||||||||:..|:::        .|:..||.|:||::.      |.|...:...||.....
Zfish   175 GWKNSIRHNLSLHSRFIRV--------QNEGTGKSSWWMINP------EGGRGGKAPRRRAVSMD 225

  Fly   199 HPNRYER-------------ESGKDSNDGNSSAAEIR----SPSEPLSDFDIFCNERPNYSDRIT 246
            :.|:|.:             ::.::.:..|.||..:.    ||:...||....|     ::|
Zfish   226 NGNKYTKTARGRAAKKKAALQAAQEGSLENISAGGLSKWPGSPTSRSSDEQESC-----WTD--- 282

  Fly   247 DLHRQYLSVSLGFNSLFNNEAR----GLRPL---PEIRECPDDVDASSSSSKAMQSSMELHEELH 304
                        |.|..|:.|.    .|.|:   ||:    |||......|..:.|
Zfish   283 ------------FRSRTNSNASTVSGRLSPILANPEL----DDVSDGPPLSPILYS--------- 322

  Fly   305 SPSAFTPPLNRRETSSSG------APVLA---------EAFNGIKDVVD--------APGSSPVA 346
            |||:.:||   ..|||:.      .||||         ||.|.:.|::|        ...|||.:
Zfish   323 SPSSLSPP---SSTSSNSKTCPGELPVLADLTGTMNLNEADNLMVDLLDNIATQVQVVQESSPFS 384

  Fly   347 ------SSNRSKTTLFTIDNIIG 363
                  :|..|.:|..|:.|..|
Zfish   385 FGSKSTASPPSTSTSQTVSNNTG 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_523912.1	FH_FOX	89..186	CDD:469596	37/101 (37%)
foxo3b	NP_571160.1	FH_FOXO1	118..216	CDD:410834	40/119 (34%)
		FOXO_KIX_bdg	411..493	CDD:465228
		FOXO-TAD	586..624	CDD:435506