Protein Alignment FoxL1 and foxa2

DIOPT Version :9

• Sequence 1: NP_001246609.1
• Gene: FoxL1 / 38471
• FlyBaseID: FBgn0004895
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_571024.1
• Gene: foxa2 / 30126
• ZFINID: ZDB-GENE-980526-404
• Length: 409
• Species: Danio rerio
• Alignment Length: 434
• Identity: 121/434 - (27%)
• Similarity: 181/434 - (41%)
• Gaps: 134/434 - (30%)

  Fly     3 PSCYA--------------------NGSMLPDNEELVNSMLANPDYLRTQVSP-----NPLAPSA 42
            |.||.                    :|.....|....|:|  |..|:.|.:||     :|...:.
Zfish    23 PECYTSVSNMNTGLGMNSMNTYMTMSGMSSTANMTAANTM--NMSYVNTGMSPSMTGMSPGTGAM 85

  Fly    43 VG-GAGMEGLMCGSFSPAF--------------YYQGIDSFLALHNNIWGLPISFLHNSHRPE-- 90
            .| ||||.| |..:.||..              .|..:::...::..      |.::.|..|:
Zfish    86 AGMGAGMTG-MSAALSPTMSPMAAQAPSMNALTSYSNMNAMSPMYGQ------SNINRSRDPKTY 143

  Fly    91 -------KPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDC 148
                   |||:|||:||.|||..:|::.||||.||::|||.||:||:|:|.|||||||:||.|||
Zfish   144 RRSYTHAKPPYSYISLITMAIQQSPSKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDC 208

  Fly   149 FVKIPRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRHCGHPNRYERESGKDSND 213
            |:|:||..      |..||||:|.|...:.:|||.|.|.||:.|.:  |  ..:..::..:.:::
Zfish   209 FLKVPRSP------DKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK--C--DKKLSKDPSRKTSE 263

  Fly   214 GNSSAAEIRSPSEPLSDFDIFCNERPNYSDRITDLHRQYLSVSLGFNSLFNNEARGLRPLPEIRE 278
            |.|:     |.||..:.     ||.|:.:....:|.|....:..|         :||.|
Zfish   264 GGSN-----SSSESCNG-----NESPHSNSSSNELKRSLSDMKSG---------QGLSP------ 303

  Fly   279 CPDDVDASSSSSK----AMQSSMELHEELHSPS---AFTPPLNRRETSSS--------------- 321
               |..||.:|..    |...|:..||....|.   :|..|.:.....||
Zfish   304 ---DHAASPTSQAQHLLAQHHSVLAHEGHLKPEHHYSFNHPFSINNLMSSEQQHHKMDLKTYEQV 365

  Fly   322 -----GAPV---LAEAFNGIKDVVDAPGSS--------PVASSN 349
                 |:|:   |:......|..:|:|.:|        |:.:|:
Zfish   366 MHYGYGSPMAGTLSMGSMASKAGLDSPDTSYYQGVYSRPILNSS 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	53/93 (57%)
foxa2	NP_571024.1	Forkhead_N	18..150	CDD:254796	26/135 (19%)
		FH	151..239	CDD:214627	53/93 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	250..315		18/92 (20%)
		HNF_C	340..398	CDD:286443	10/57 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910