Protein Alignment FoxL1 and FOXL1

DIOPT Version :10

• Sequence 1: NP_523912.1
• Gene: FoxL1 / 38471
• FlyBaseID: FBgn0004895
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_005241.1
• Gene: FOXL1 / 2300
• HGNCID: 3817
• Length: 345
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 116/334 - (34%)
• Similarity: 146/334 - (43%)
• Gaps: 104/334 - (31%)

  Fly    57 SPAFYYQGIDSFLALHNNIWGLPISF-----LHNSHR---PEKPPFSYIALIAMAISSAPNQRLT 113
            ||..|..|.:.        .|||::|     |..|.|   |:|||:||||||||||..||.||:|
Human    15 SPMLYLYGPER--------PGLPLAFAPAAALAASGRAETPQKPPYSYIALIAMAIQDAPEQRVT 71

  Fly   114 LSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDSSAS 178
            |:|||:||||:||:|.:|:|||||||||||||||||||:||:|.      ..||||||.||....
Human    72 LNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKG------RPGKGSYWTLDPRCL 130

  Fly   179 DMFEQGNYRRRR-----------TRRQRHCGHPNRYERESGKDSNDGNSSAAEIRSPSEPLSDFD 232
            ||||.||||||:           .:|.|...|....|.:....|..|.|..|..|..:.|.....
Human   131 DMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSP 195

  Fly   233 IFCNERPNYSDRITDLHRQYLSVSLGFNSLFNNEARGLRPLPEIRECPDDVDASSSSSKAMQSSM 297
            :.....|                                |.|
Human   196 LLDGPSP--------------------------------PAP----------------------- 205

  Fly   298 ELHEELHSPSAFTPPLNRRETSSSGAPVLAEAFNGIKDVVDAPGSSPVASSNRS------KTTLF 356
                 ||.|...:|..:..:.:...|.|   |........|.|| ||:..::||      |:..|
Human   206 -----LHWPGTASPNEDAGDAAQGAAAV---AVGQAARTGDGPG-SPLRPASRSSPKSSDKSKSF 261

  Fly   357 TIDNII-GK 364
            :||:|: ||
Human   262 SIDSILAGK 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_523912.1	FH_FOX	89..186	CDD:469596	66/96 (69%)
FOXL1	NP_005241.1	FH_FOXL1	47..144	CDD:410801	71/102 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..289		40/199 (20%)