Protein Alignment FoxL1 and FOXJ3

DIOPT Version :10

• Sequence 1: NP_523912.1
• Gene: FoxL1 / 38471
• FlyBaseID: FBgn0004895
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: XP_005270689.1
• Gene: FOXJ3 / 22887
• HGNCID: 29178
• Length: 630
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 97/332 - (29%)
• Similarity: 141/332 - (42%)
• Gaps: 89/332 - (26%)

  Fly    87 HRPEKPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVK 151
            |:..|||:||.:||..||:|:|.:::|||.||::|.|.||||||...||:||||||||||.||:|
Human    82 HKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLK 146

  Fly   152 IPRDKNTIEDNDSAGKGSYWMLDSS-ASDMFEQGNYRRRRTRRQRHCGHPNRYERESGKDSNDGN 215
            :||.|      |..||||||.:|:: ..|:......:|.|:           .||.|...|.|.:
Human   147 VPRSK------DDPGKGSYWAIDTNPKEDVLPTRPKKRARS-----------VERASTPYSIDSD 194

  Fly   216 SSAAE--IRSPSEPLSDFDIFCNERPNY-SDRI-TDLHRQYLSVSLGFNSLFN---NEARGLRPL 273
            |...|  |...:.|....:...|:...| :|:. :|..|..|:.||...||.:   |....:...
Human   195 SLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSY 259

  Fly   274 PEIRECPDDVDAS----------------------------SSSSKAM----------------- 293
            ..:...|:.|..|                            |:|.:::
Human   260 TPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNI 324

  Fly   294 --QSSMELHEEL---HSPSAFT---PPLNRRETSSSGAPVLAEAFNGIKDVVDAPGSSPVASSNR 350
              :||.:.|...   ||||:..   |..|:...|:|....|           :..||:.||..:.
Human   325 PSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGL-----------NTTGSNSVAQVSL 378

  Fly   351 SKTTLFT 357
            |...:.|
Human   379 SHPQMHT 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_523912.1	FH_FOX	89..186	CDD:469596	51/97 (53%)
FOXJ3	XP_005270689.1	COG5025	<62..343	CDD:227358	84/277 (30%)
		FH_FOXJ3	85..163	CDD:410826	49/83 (59%)
		KLF1_2_4_N	<380..450	CDD:425360	1/6 (17%)