Protein Alignment FoxL1 and Foxa2

DIOPT Version :10

• Sequence 1: NP_523912.1
• Gene: FoxL1 / 38471
• FlyBaseID: FBgn0004895
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_001277994.1
• Gene: Foxa2 / 15376
• MGIID: 1347476
• Length: 465
• Species: Mus musculus
• Alignment Length: 314
• Identity: 101/314 - (32%)
• Similarity: 142/314 - (45%)
• Gaps: 59/314 - (18%)

  Fly    33 VSP--NPLAPSAVGGAGMEGLM----CGSFSPAFYYQGIDSFLALHNNIWGLPISFLHNSHRPEK 91
            :||  :||...|.|..|  ||.    ..|.||.:...|:.....        |.:: ..|:...|
Mouse   112 LSPSLSPLGGQAAGAMG--GLAPYANMNSMSPMYGQAGLSRARD--------PKTY-RRSYTHAK 165

  Fly    92 PPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRDK 156
            ||:|||:||.|||..:||:.||||.||::|||.||:||:|:|.|||||||:||.||||:|:||..
Mouse   166 PPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSP 230

  Fly   157 NTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRHCGHPNRYERESGKDSNDGNSSAAEI 221
                  |..||||:|.|...:.:|||.|.|.||:.|.:  |......:..:|..|:.|..:|...
Mouse   231 ------DKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK--CEKQLALKEAAGAASSGGKKTAPGS 287

  Fly   222 RSPSEPLSDFDIFCN------ERPNYSDRITDLHRQYLSVSLGFNSLFNNEARGLRPLPEIRECP 280
            ::....|.:.....:      |.|:.|......|::.     |.:.|....|..|.| ||
Mouse   288 QASQAQLGEAAGSASETPAGTESPHSSASPCQEHKRG-----GLSELKGAPASALSP-PE----- 341

  Fly   281 DDVDASSSSSKAMQSSMELHEELHSPS-------------AFTPPLNRRETSSS 321
                .:.|..:..|::..|....|.|.             ||..|.:.....||
Mouse   342 ----PAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLMSS 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_523912.1	FH_FOX	89..186	CDD:469596	55/96 (57%)
Foxa2	NP_001277994.1	Forkhead_N	23..164	CDD:369872	15/62 (24%)
		FH_FOXA2	163..264	CDD:410813	59/108 (55%)
		PRK07764	<266..>354	CDD:236090	18/102 (18%)
		HNF_C	380..454	CDD:430552	3/12 (25%)