DRSC/TRiP Functional Genomics Resources

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Protein Alignment FoxL1 and Foxd1

DIOPT Version :9

Sequence 1:NP_001246609.1 Gene:FoxL1 / 38471 FlyBaseID:FBgn0004895 Length:365 Species:Drosophila melanogaster
Sequence 2:NP_032268.2 Gene:Foxd1 / 15229 MGIID:1347463 Length:456 Species:Mus musculus


Alignment Length:396 Identity:123/396 - (31%)
Similarity:167/396 - (42%) Gaps:104/396 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 LPS-------CYANGSMLPDNEELVNS--MLANPDYLRTQVSPNPLAPSAVGGAGMEGLM-CGSF 56
            |||       .||....|.|.||..:.  :||:    |...||.|..|:...|.|..|.. .|:.
Mouse    49 LPSSAQRRRRSYAGEDDLEDLEEEDDDDLLLAS----RPAASPAPPGPAPAPGTGSGGCSGAGAG 109

  Fly    57 SPAFYYQGIDSFLALHNNIWGLPISFLHNSHRPEKPPFSYIALIAMAISSAPNQRLTLSGIYKFI 121
            ..|....|..:.....|.:              .|||:||||||.|||..:|.:|||||.|.:||
Mouse   110 GGAGGGTGAGTGGGAKNPL--------------VKPPYSYIALITMAILQSPKKRLTLSEICEFI 160

  Fly   122 MDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNY 186
            ..:||||||....||||||||||||||||||||:..      :.|||:||.||..::|||:.|::
Mouse   161 SSRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPG------NPGKGNYWTLDPESADMFDNGSF 219

  Fly   187 RRRRTRRQR------HCGHPNRYERESGKDSNDGNSSAAEIRSPSEPLSDFDIFCNERPNYSDRI 245
            .|||.|.:|      |........|.:|..:..|:..||....|..|                  
Mouse   220 LRRRKRFKRQPLLAPHAAAEALLLRGAGPAAGAGDPGAALFPPPPPP------------------ 266

  Fly   246 TDLHRQYLSVSLGFNSLFNNEARGLRPLPEIREC--PDDVDASSSSSKAMQSSMELHEELHSPSA 308
                     .:.|:.:.  ..|.||:..|    |  |..:.|:::::.|    ...|.  |||..
Mouse   267 ---------PACGYGAY--GCAYGLQLPP----CAPPSALFAAAAAAAA----AAFHP--HSPPP 310

  Fly   309 FTPPLN---------RRETSSSGAPVLAEAFNG------IKDVVDAPGSSPVASSNRSKTTLFTI 358
            ..||..         .|......:..||.|..|      :|  ...||::.:|.|.      |:|
Mouse   311 PPPPPPPPPGAAAELARTAFGYRSHALAAALPGPLQAAAVK--AGGPGAAALARSP------FSI 367

  Fly   359 DNIIGK 364
            :::||:
Mouse   368 ESLIGR 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FoxL1NP_001246609.1 FH 91..185 CDD:214627 57/93 (61%)
Foxd1NP_032268.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..104 19/58 (33%)
Forkhead 130..216 CDD:278670 57/91 (63%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 303..322 6/20 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 381..401
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.910

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