DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxL1 and Foxf2

DIOPT Version :9

Sequence 1:	NP_001246609.1	Gene:	FoxL1 / 38471	FlyBaseID:	FBgn0004895	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_034355.2	Gene:	Foxf2 / 14238	MGIID:	1347479	Length:	446	Species:	Mus musculus

Alignment Length:	313	Identity:	102/313 - (32%)
Similarity:	142/313 - (45%)	Gaps:	94/313 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 RPEKPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKI 152
            ||||||:||||||.|||.|:|::|||||.||:|:..:||::|...|||:||:|||||||:||:|:
Mouse    97 RPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKL 161

  Fly   153 PRDKNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRHCG--HPNRYERESGKDSN--- 212
            |:...      ..|||.||.:|.::..|||:|::|||....:|.|.  .|..:...||....
Mouse   162 PKGLG------RPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGFGASL 220

  Fly   213 --DGNSSAAEIRSPSEPLSDFDIFCNERPNYSDRITDLHRQYLSVSLGFNS------------LF 263
              .|....|   .||.||.     |:.:..|..  .|:      :..|:::            |.
Mouse   221 LPQGFDFQA---PPSAPLG-----CHGQGGYGG--LDM------MPAGYDTGAGAPGHAHPHHLH 269

  Fly   264 NNEARGLRPLP---EIRECPDDV--------------------DASSS---SSKAMQSSMELHEE 302
            ::....:.|.|   .:..||...                    |:|||   ||.||.|::|.|..
Mouse   270 HHHVPHMSPNPGSTYMASCPVPAGPAGVGAAAGGGGGGGDYGPDSSSSPVPSSPAMASAIECHSP 334

  Fly   303 LHSPSAFTPPLNRRETSSSGA-------PVLAEAFNGIKDVVDAPGSSPVASS 348
            ..||:|        ..||.||       |.|            .|.|:|.||:
Mouse   335 YTSPAA--------HWSSPGASPYLKQPPAL------------TPSSNPAASA 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	50/93 (54%)
Foxf2	NP_034355.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..97		102/313 (33%)
		FH	100..188	CDD:214627	50/93 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	257..278		1/20 (5%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	304..325		6/20 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	340..371		12/48 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900