DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxL1 and Foxd4

DIOPT Version :9

Sequence 1:	NP_001246609.1	Gene:	FoxL1 / 38471	FlyBaseID:	FBgn0004895	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_032048.1	Gene:	Foxd4 / 14237	MGIID:	1347467	Length:	444	Species:	Mus musculus

Alignment Length:	226	Identity:	86/226 - (38%)
Similarity:	111/226 - (49%)	Gaps:	58/226 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VNSMLANPDYLRTQVSPNPLA---------------------------------------PSAVG 44
            :||  |...:||:...|:||:                                       |.|..
Mouse     1 MNS--ARAGHLRSTPPPSPLSSDQDEVEIDVLAEEEDGDQTEEEDDEEESHKCLERSLQRPGART 63

  Fly    45 GAGMEGLMCGSFSPAFYYQGIDSFLALHNNIWGLPISFLHNSHRPEKPPFSYIALIAMAISSAPN 109
            .||.....||..|.:..:  :..|.|...     |.:...:..:|.|||:||||||.|||..:|:
Mouse    64 LAGRSAGDCGDLSNSSGF--LRKFRAPRT-----PATTTADGPQPAKPPYSYIALITMAILQSPH 121

  Fly   110 QRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRDKNTIEDNDSAGKGSYWMLD 174
            :|||||||..||..:|||||.....||||||||||||||||||||:..      ..|||:||.||
Mouse   122 KRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPG------HPGKGNYWSLD 180

  Fly   175 SSASDMFEQGNYRRRRTRRQRH----CGHPN 201
            .::.|||:.|::.|||.|.:||    .|||:
Mouse   181 PASQDMFDNGSFLRRRKRFKRHHPPSGGHPH 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	57/93 (61%)
Foxd4	NP_032048.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..70		12/70 (17%)
		Forkhead	103..189	CDD:278670	57/91 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	234..256
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820