DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxL1 and foxe1

DIOPT Version :9

Sequence 1:	NP_001246609.1	Gene:	FoxL1 / 38471	FlyBaseID:	FBgn0004895	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	XP_002936729.1	Gene:	foxe1 / 100038190	XenbaseID:	XB-GENE-478544	Length:	377	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	94/286 - (32%)
Similarity:	137/286 - (47%)	Gaps:	52/286 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 KPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRD 155
            |||:||||||||||:::.:::|||.||||||.::||:||:|.:.|||||||||:|||||:||||:
Frog    66 KPPYSYIALIAMAIANSTDRKLTLGGIYKFITERFPFYRDNSKKWQNSIRHNLTLNDCFIKIPRE 130

  Fly   156 KNTIEDNDSAGKGSYWMLDSSASDMFEQGNYRRRRTRRQRHCGHPNRYERESGKDSNDGNSSAAE 220
            ..      ..|||:||.||.:|.|||:.|::.|||.|.:|                .|..:..|.
Frog   131 PG------RPGKGNYWALDPNAEDMFDSGSFLRRRKRFKR----------------TDLTTYPAY 173

  Fly   221 IRSPS--EPLS------DFDIFCN--ERPNYSDRITDLHRQYLSVS-----------LGFNSLFN 264
            |...|  .||.      ...::.|  ..|:||.:|......|...|           ...|:|..
Frog   174 IHDTSMFSPLQVARATYPNTVYPNMTMSPSYSQQIAPHSSVYYPSSSPAFSSAQPRVFSINTLIG 238

  Fly   265 NEARGLRPLPEIRECPDDVDASSSSS--------KAMQSSMELHEELHSPSAFTPPLNRRETSSS 321
            :........|. |....:|:::||||        .:...|..:.....:|.:::.|.:..:.:.|
Frog   239 HSGSEHAQQPN-RSISPEVNSTSSSSCNYGGSTYSSQAGSGTMLPRSTNPYSYSVPNSHLQMNQS 302

  Fly   322 GAPVLAEAFNGIKDVVDAPGSSPVAS 347
            ..|.......|....:..|.|.|:.|
Frog   303 SYPHSNAQLFGSASRLPMPTSPPMNS 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	56/93 (60%)
foxe1	XP_002936729.1	FH	66..154	CDD:214627	56/93 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010