DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxL1 and foxl3

DIOPT Version :9

Sequence 1:	NP_001246609.1	Gene:	FoxL1 / 38471	FlyBaseID:	FBgn0004895	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001182055.1	Gene:	foxl3 / 100003253	ZFINID:	ZDB-GENE-121214-362	Length:	220	Species:	Danio rerio

Alignment Length:	224	Identity:	87/224 - (38%)
Similarity:	112/224 - (50%)	Gaps:	50/224 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 KPPFSYIALIAMAISSAPNQRLTLSGIYKFIMDKFPYYRENKQGWQNSIRHNLSLNDCFVKIPRD 155
            :|.:||||||||||..:|..::||||||:|||.:|||||.|::.||||||||||||.||:|:||
Zfish    33 RPAYSYIALIAMAIQQSPENKVTLSGIYEFIMKRFPYYRSNQRAWQNSIRHNLSLNSCFIKVPR- 96

  Fly   156 KNTIEDNDSAGKGSYWMLDS---SASDMFEQGNYRRRRTRRQRHCGHPNRYERESGKDSNDGNSS 217
               .|.|:. |||:||...:   |..|:||.||:||||.||....|.....|.....|::    .
Zfish    97 ---TEGNEK-GKGNYWTFATGCESMLDLFENGNFRRRRRRRNLKMGLKEPTEAFISMDAH----Q 153

  Fly   218 AAEIRSPSEPLSDFDIFCNERPNYSDRITDLHRQYLSVSLGFNSLFNNEARGLRPLPEIR----- 277
            |..:||     ||.|.|.|..          ||                |...:|..||:
Zfish   154 AVAVRS-----SDSDSFMNTS----------HR----------------AAQNKPETEIKFSIDY 187

  Fly   278 --ECPDDVDASSSSSKAMQSSMELHEELH 304
              ..||.:.|..:.:.|:......|..||
Zfish   188 ILSTPDPLPAFRAPNSAIPHLEPQHLNLH 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxL1	NP_001246609.1	FH	91..185	CDD:214627	55/96 (57%)
foxl3	NP_001182055.1	Forkhead	33..119	CDD:278670	52/90 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920