DRSC/TRiP Functional Genomics Resources

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Protein Alignment scrt and SCRT2

DIOPT Version :9

Sequence 1:NP_001261390.1 Gene:scrt / 38469 FlyBaseID:FBgn0004880 Length:653 Species:Drosophila melanogaster
Sequence 2:NP_149120.1 Gene:SCRT2 / 85508 HGNCID:15952 Length:307 Species:Homo sapiens


Alignment Length:262 Identity:140/262 - (53%)
Similarity:166/262 - (63%) Gaps:41/262 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   364 EQRPASNASSASSNHMPSSPSSNSSSSSSQVQNENSNTTNTNPDGDGCLQDGEHSGAS-----GA 423
            :|:|....:.|...:.|::|...|...|.|                        |..|     |.
Human    59 DQKPGLELAPAEPAYPPAAPEEYSDPESPQ------------------------SSLSARYFRGE 99

  Fly   424 SAKTVAYTYEAFFVSDGRSKRKH---------VADPAAAASGVPTPDQQK---TKYTCSECGKQY 476
            :|.|.:|:.:|||:|||||:|:.         ..|...|.........|.   .::.|:||||.|
Human   100 AAVTDSYSMDAFFISDGRSRRRRGGGGGDAGGSGDAGGAGGRAGRAGAQAGGGHRHACAECGKTY 164

  Fly   477 ATSSNLSRHKQTHRSLDSQSAKKCHTCGKAYVSMPALAMHLLTHKLSHSCGVCGKLFSRPWLLQG 541
            |||||||||||||||||||.|:||.|||||||||||||||||||.|.|.||||||.|||||||||
Human   165 ATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHLLTHNLRHKCGVCGKAFSRPWLLQG 229

  Fly   542 HLRSHTGEKPYGCAHCGKAFADRSNLRAHMQTHSVDKNFECKRCHKTFALKSYLNKHLESACLKD 606
            |:||||||||:|||||||||||||||||||||||..|::.|::|.|:|||||||:||.|:||.|.
Human   230 HMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYLHKHCEAACAKA 294

  Fly   607 EE 608
            .|
Human   295 AE 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scrtNP_001261390.1 zf-C2H2 467..489 CDD:278523 17/21 (81%)
C2H2 Zn finger 469..489 CDD:275370 17/19 (89%)
C2H2 Zn finger 500..520 CDD:275368 18/19 (95%)
COG5048 520..>617 CDD:227381 68/89 (76%)
C2H2 Zn finger 526..546 CDD:275368 17/19 (89%)
zf-H2C2_2 539..562 CDD:290200 20/22 (91%)
C2H2 Zn finger 554..574 CDD:275368 19/19 (100%)
zf-C2H2 554..574 CDD:278523 19/19 (100%)
zf-H2C2_2 566..590 CDD:290200 14/23 (61%)
C2H2 Zn finger 582..599 CDD:275368 11/16 (69%)
SCRT2NP_149120.1 SNAG domain. /evidence=ECO:0000250 1..20
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..90 8/54 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 116..148 6/31 (19%)
C2H2 Zn finger 157..177 CDD:275368 17/19 (89%)
COG5048 <210..>277 CDD:227381 53/66 (80%)
C2H2 Zn finger 214..234 CDD:275368 17/19 (89%)
zf-H2C2_2 227..250 CDD:290200 20/22 (91%)
C2H2 Zn finger 242..262 CDD:275368 19/19 (100%)
zf-H2C2_2 254..278 CDD:290200 14/23 (61%)
C2H2 Zn finger 270..286 CDD:275368 10/15 (67%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165147582
Domainoid 1 1.000 53 1.000 Domainoid score I11355
eggNOG 1 0.900 - - E1_KOG2462
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1332418at2759
OrthoFinder 1 1.000 - - FOG0000984
OrthoInspector 1 1.000 - - mtm8640
orthoMCL 1 0.900 - - OOG6_107036
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3156
SonicParanoid 1 1.000 - - X1445
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1110.640

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