DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scrt and Zfp566

DIOPT Version :9

Sequence 1:	NP_001261390.1	Gene:	scrt / 38469	FlyBaseID:	FBgn0004880	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_001128198.1	Gene:	Zfp566 / 502316	RGDID:	1563239	Length:	386	Species:	Rattus norvegicus

Alignment Length:	290	Identity:	79/290 - (27%)
Similarity:	118/290 - (40%)	Gaps:	42/290 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 HYLPLQQQQQQQ-----AHHTHLPTLEAHAHLRSTSSIAELAAAASVVNEQRPASNASSASSNHM 379
            |...|:..|::|     .:...:|||..:..||...::..        .|:..||..:.....|.
  Rat    95 HCERLRGSQERQFSELIINREDVPTLSHYPSLRLQQTVRS--------KEKYCASKENRQHCKHA 151

  Fly   380 P-SSPSSNSSSSSSQVQNENSNTTNTNPDGDGCLQDGE--HSGASGASAKTVAYTYEAFFVSD-G 440
            . .||.....::....:.::...|..:|.|   |....  |:|......|....|:  ...|| .
  Rat   152 SLFSPHQIIRTTEKPYECKDCGKTFRHPSG---LTHHHKIHTGKKPFECKECGKTF--ICGSDLT 211

  Fly   441 RSKRKHVADPAAAASGVPTPDQQKTKYTCSECGKQYATSSNLSRHKQTHRSLDSQSAKKCHTCGK 505
            |..|.|..:               ..|.|.:|||.:::.||.:||::.|   ..:...:|..|||
  Rat   212 RHHRIHTGE---------------KPYECKDCGKAFSSGSNFTRHQRIH---TGEKPYECKECGK 258

  Fly   506 AYVSMPALAMHLLTH--KLSHSCGVCGKLFSRPWLLQGHLRSHTGEKPYGCAHCGKAFADRSNLR 568
            |:.|......|...|  :..:.|..||..||:...|..|.|.|||||||.|..|.|||...|:|.
  Rat   259 AFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLT 323

  Fly   569 AHMQTHSVDKNFECKRCHKTFALKSYLNKH 598
            .|.:.|:.:|.:|||.|.|.::..|.|..|
  Rat   324 RHQRIHTGEKPYECKICGKAYSQSSQLISH 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scrt	NP_001261390.1	zf-C2H2	467..489	CDD:278523	9/21 (43%)
		C2H2 Zn finger	469..489	CDD:275370	8/19 (42%)
		C2H2 Zn finger	500..520	CDD:275368	7/19 (37%)
		COG5048	520..>617	CDD:227381	34/81 (42%)
		C2H2 Zn finger	526..546	CDD:275368	8/19 (42%)
		zf-H2C2_2	539..562	CDD:290200	14/22 (64%)
		C2H2 Zn finger	554..574	CDD:275368	8/19 (42%)
		zf-C2H2	554..574	CDD:278523	8/19 (42%)
		zf-H2C2_2	566..590	CDD:290200	9/23 (39%)
		C2H2 Zn finger	582..599	CDD:275368	7/17 (41%)
Zfp566	NP_001128198.1	KRAB	5..45	CDD:396083
		zf-C2H2	167..189	CDD:395048	4/24 (17%)
		C2H2 Zn finger	169..189	CDD:275368	4/22 (18%)
		COG5048	<193..355	CDD:227381	58/181 (32%)
		C2H2 Zn finger	197..217	CDD:275368	6/21 (29%)
		C2H2 Zn finger	225..245	CDD:275368	8/19 (42%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		C2H2 Zn finger	281..301	CDD:275368	8/19 (42%)
		C2H2 Zn finger	309..329	CDD:275368	8/19 (42%)
		C2H2 Zn finger	337..357	CDD:275368	7/17 (41%)
		C2H2 Zn finger	365..384	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I4772
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050