DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment scrt and ZIPIC

DIOPT Version :9

Sequence 1:NP_001261390.1 Gene:scrt / 38469 FlyBaseID:FBgn0004880 Length:653 Species:Drosophila melanogaster
Sequence 2:NP_651765.1 Gene:ZIPIC / 43566 FlyBaseID:FBgn0039740 Length:457 Species:Drosophila melanogaster


Alignment Length:418 Identity:86/418 - (20%)
Similarity:144/418 - (34%) Gaps:108/418 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   245 IYRPYSLDDKPAHGYRRRVPAEEDLHAAHAILDLSASTAFHPPTQPHQLQQQQQQQQQQHQHHHS 309
            |:.||...|.....|:     |:||.....|.....:.            ::.|||.::.|...|
  Fly    79 IHSPYMSKDHKQTSYK-----EDDLDRETTISKFDGNI------------EEAQQQDEEEQELES 126

  Fly   310 Q------------QQHLAPQQHHYLPLQQQQQQQAHHTHLP--------TLEAHAHLRSTSSIA- 353
            .            .:.:|.::|.::..|.:::.:.|...|.        ..|..||  ....:| 
  Fly   127 VGTTVTLVGPAGIVEEVAEEEHTFIIKQSEEEDEFHSVDLELDIDNEIIINEEEAH--EVEEVAH 189

  Fly   354 ELAAAASVVNEQRPASNASSASSNHMPSSPSSNSSSSSSQVQNENSNTTNTNPDG----DGCLQ- 413
            |:...|..:.|:           :.:|        ....:.|.|:....:|..|.    ||.:: 
  Fly   190 EIEEVAHEIEEE-----------DLLP--------HDKQEAQEEDFFKEDTMSDFDEHLDGAIEY 235

  Fly   414 ---DGEHSGASGASAKTVAYTYEAFFVSDGRSKRKHVADPAAAASGVPTPDQQKTKYTCSECGKQ 475
               |||.......|:.......:.....:..|.|:        |..|.|..:....|.|.:|||.
  Fly   236 IISDGEDQEQDNESSGEYTVNIQCPSCPEKFSSRR--------AYNVHTKREHFPGYVCDQCGKT 292

  Fly   476 YATSSNLSRHKQTHRSL-------------------------DSQSAKKCHTCGKAYVSMPALAM 515
            ..:.|....|.|.|..:                         ..::..:|..|.|.:|...||..
  Fly   293 LQSYSGFIGHLQNHEPVKQFACPVCPERFSRKFRLKHHMAWHSGETPYQCDVCSKRFVHKVALYK 357

  Fly   516 HLLTHKLSH---SCGVCGKLFSRPWLLQGHLRSHTGEKPYGCAHCGKAFADRSNLRAHMQTH--- 574
            |.:.|....   .|.|||........|:.|:|||||:||:.|..|.|.|:...|::||::.|   
  Fly   358 HKMIHDSETKRLECQVCGFKTRTKAHLERHMRSHTGDKPFACPVCNKRFSQMYNMKAHLREHESP 422

  Fly   575 --SVDKNFECKRCHKTFALKSYLNKHLE 600
              :..:.|.|.:|..||..:...:.|::
  Fly   423 GTNRHRRFHCSKCTHTFINEQNYDAHVQ 450

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scrtNP_001261390.1 zf-C2H2 467..489 CDD:278523 8/21 (38%)
C2H2 Zn finger 469..489 CDD:275370 7/19 (37%)
C2H2 Zn finger 500..520 CDD:275368 7/19 (37%)
COG5048 520..>617 CDD:227381 28/89 (31%)
C2H2 Zn finger 526..546 CDD:275368 7/19 (37%)
zf-H2C2_2 539..562 CDD:290200 12/22 (55%)
C2H2 Zn finger 554..574 CDD:275368 7/19 (37%)
zf-C2H2 554..574 CDD:278523 7/19 (37%)
zf-H2C2_2 566..590 CDD:290200 8/28 (29%)
C2H2 Zn finger 582..599 CDD:275368 4/16 (25%)
ZIPICNP_651765.1 C2H2 Zn finger 286..306 CDD:275368 7/19 (37%)
C2H2 Zn finger 314..334 CDD:275368 0/19 (0%)
zf-H2C2_2 327..351 CDD:290200 3/23 (13%)
C2H2 Zn finger 342..391 CDD:275368 15/48 (31%)
zf-H2C2_2 383..408 CDD:290200 13/24 (54%)
C2H2 Zn finger 399..419 CDD:275368 7/19 (37%)
C2H2 Zn finger 432..449 CDD:275368 4/16 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457097
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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