DRSC/TRiP Functional Genomics Resources

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Protein Alignment scrt and MTF-1

DIOPT Version :9

Sequence 1:NP_001261390.1 Gene:scrt / 38469 FlyBaseID:FBgn0004880 Length:653 Species:Drosophila melanogaster
Sequence 2:NP_001097560.1 Gene:MTF-1 / 39089 FlyBaseID:FBgn0040305 Length:1006 Species:Drosophila melanogaster


Alignment Length:640 Identity:131/640 - (20%)
Similarity:206/640 - (32%) Gaps:258/640 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   177 ARTSGNGSGDQHLAAYQTPPS--STTSSP----SCSPSGA------------------------G 211
            |.:.||...|..  .|.|..|  |.:.||    :||.||:                        |
  Fly    24 ANSHGNSLSDSR--DYDTNSSRNSLSGSPPVTSNCSSSGSLDFDRPLAQLLEPKLEADGLGIIHG 86

  Fly   212 DRYSPLSS---GQTSSERKCFSSTGATLSLPPKKKDIYRPYSLDDKPAHGYRRRVPAEEDLHAAH 273
            |.||...|   ..||.|::.. :.|.||.            :.|.:..:|         ||..| 
  Fly    87 DNYSIYGSQTAESTSGEQQVL-NLGLTLD------------TGDAQATYG---------DLFGA- 128

  Fly   274 AILDLSASTAFHPPTQPHQLQQQQQQQQQQHQHHHSQ-------------QQHLAPQQHHYLPLQ 325
                                   |.|......|.|||             ...|.|.....:|:.
  Fly   129 -----------------------QDQLTASQTHGHSQVVVSAAADNAFSLADQLTPLPITVIPIT 170

  Fly   326 QQQQQQAHHTHLPTLEAHAHLRSTSSIAELAA------------------------------AAS 360
            .      |||......:|:.:...:|::::.|                              :.|
  Fly   171 Y------HHTTENLSSSHSEVPLIASLSDITAQVFNLDDICFTLEYQFENQRLVQVQPPTVVSLS 229

  Fly   361 VVNEQRPASNA------SSASSNHMPSSPSSNSSS----SSSQVQNENSNTTNTNPDGD----GC 411
            :|:....|:|.      ...:.|.:....:|||.:    .:|.|...:.|    .||.|    .|
  Fly   230 MVSSPNEAANPPINCDNDQGTGNSISRDSTSNSPAYFTIETSYVDEYDPN----EPDEDEQLAHC 290

  Fly   412 LQDG--------EHSGASGASAKTVAYTYEAFFVSDGRSKRKHVADPAAAASGVPTPDQQKTKYT 468
            :|.|        |.......:.:.:|..||                         :.|:..::|.
  Fly   291 IQPGVLHQDVDEEEVERQDENDQLMALAYE-------------------------SSDEALSRYR 330

  Fly   469 CS--ECGKQYATSSNLSRHKQTHRS---------------LDSQSAK---KCHT----------- 502
            |:  .|.:.|:|..||..|.:||..               |.|.|.|   :.||           
  Fly   331 CNYENCYRSYSTIGNLRTHLKTHTGDYSFKCPEDGCHKAFLTSYSLKIHVRVHTKVKPYECEVSG 395

  Fly   503 CGKAYVSMPALAMHLLTHK-LSHSCGVCGKLFSRPWLLQGHLRSHTGEKPYGCAH--CGKAFADR 564
            |.||:.:...|..||..|. .:.:|.:|.|.|:....|:.|:|:||.|:||.|..  |||||...
  Fly   396 CDKAFNTRYRLHAHLRLHNGETFNCELCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTAS 460

  Fly   565 SNLRAHMQTHSVDKNFECKR--CHKTF----ALKSYLNKHL------------------------ 599
            .:|:.|.:||:.:|.:.|:.  |.|:|    :|||:...|.                        
  Fly   461 HHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLQNKGRKKRPLKTQQTKCSDQE 525

  Fly   600 ----------ESACLKDEEELMMSMSLSMHDS---NSESGASMASSPPHEFLERV 641
                      |...:|:::..|..::...|.|   :::||..:.:..|.:.|..|
  Fly   526 QKDPQQEEQEEEEFIKEDQPEMTLLNPGSHCSETTSTDSGVVLQTLTPQDHLSNV 580

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scrtNP_001261390.1 zf-C2H2 467..489 CDD:278523 8/23 (35%)
C2H2 Zn finger 469..489 CDD:275370 7/21 (33%)
C2H2 Zn finger 500..520 CDD:275368 8/30 (27%)
COG5048 520..>617 CDD:227381 35/139 (25%)
C2H2 Zn finger 526..546 CDD:275368 7/19 (37%)
zf-H2C2_2 539..562 CDD:290200 13/24 (54%)
C2H2 Zn finger 554..574 CDD:275368 8/21 (38%)
zf-C2H2 554..574 CDD:278523 8/21 (38%)
zf-H2C2_2 566..590 CDD:290200 9/29 (31%)
C2H2 Zn finger 582..599 CDD:275368 7/22 (32%)
MTF-1NP_001097560.1 zf-C2H2_aberr 329..471 CDD:293622 44/141 (31%)
C2H2 Zn finger 331..353 CDD:275368 7/21 (33%)
zf-H2C2_2 345..372 CDD:290200 5/26 (19%)
C2H2 Zn finger 361..383 CDD:275368 4/21 (19%)
zf-H2C2_2 375..402 CDD:290200 7/26 (27%)
C2H2 Zn finger 391..413 CDD:275368 6/21 (29%)
zf-C2H2 418..440 CDD:278523 7/21 (33%)
C2H2 Zn finger 420..440 CDD:275368 7/19 (37%)
zf-H2C2_2 432..458 CDD:290200 13/25 (52%)
COG5048 442..>519 CDD:227381 22/76 (29%)
C2H2 Zn finger 448..470 CDD:275368 8/21 (38%)
zf-H2C2_2 462..489 CDD:290200 9/26 (35%)
C2H2 Zn finger 478..500 CDD:275368 7/21 (33%)
DUF3682 862..>931 CDD:289231
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457070
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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