DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scrt and Kah

DIOPT Version :9

Sequence 1:	NP_001261390.1	Gene:	scrt / 38469	FlyBaseID:	FBgn0004880	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	128/348 - (36%)
Similarity:	171/348 - (49%)	Gaps:	80/348 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 QQQQAHHTHLPTLEAHAHLRSTSSIAE--LAAAASVVNEQRPAS--NASSASSNHMP-------- 380
            :.|||  |.:|     ..|.:.:.:||  |:....|.:|.:|..  .:|...||:..
  Fly     3 KDQQA--TPIP-----EELYNLTQLAEVTLSVGPLVTDEVKPLPLYASSDDDSNYYSHKVFDRRK 60

  Fly   381 ----------SSPSSNSSSSSSQVQNENSNTTNTNPDGDGCLQDGEHSGASGASAKTVAYTYEAF 435
                      |..||:|||:||:..:|                  :|.|..|.|
  Fly    61 LRRCTISDSNSCASSSSSSTSSRQSSE------------------DHLGLQGHS----------- 96

  Fly   436 FVSDGRSKRKHVADPAAAASGVPTPDQQKTKYTCSECGKQYATSSNLSRHKQTHRSLDSQSAKKC 500
                  |...|..:.....:.....:.:   :.|.||||:|:|||||:||:|||||:..:.|:.|
  Fly    97 ------SVHHHHGEQGEILNSTSLLEDE---HICPECGKKYSTSSNLARHRQTHRSIMDKKARHC 152

  Fly   501 HTCGKAYVSMPALAMHLLTHKLSHSCGVCGKLFSRPWLLQGHLRSHTGEKPYGCAHCGKAFADRS 565
            ..|.|.||||||.:||:.||.....|..|||.||||||||||:|:||||||:.|..|.|||||:|
  Fly   153 PYCEKVYVSMPAYSMHVRTHNQGCECQFCGKRFSRPWLLQGHIRTHTGEKPFKCGVCEKAFADKS 217

  Fly   566 NLRAHMQTHSVDKNFECKRCHKTFALKSYLNKHLESACLKDEEELMMSMSLSMHDSNSESGASMA 630
            |||||:||||..|...|.||.|.|||||||.||.||:|:|:..        .:..|.:.||....
  Fly   218 NLRAHIQTHSNTKPHTCARCGKAFALKSYLYKHEESSCMKNRG--------GVPGSGAASGNRPP 274

  Fly   631 SSPPHEFLERVKLEGSGGATYAM 653
            |||     :|.:.|.:.|...|:
  Fly   275 SSP-----KRQQAEVTSGTISAL 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scrt	NP_001261390.1	zf-C2H2	467..489	CDD:278523	14/21 (67%)
		C2H2 Zn finger	469..489	CDD:275370	14/19 (74%)
		C2H2 Zn finger	500..520	CDD:275368	11/19 (58%)
		COG5048	520..>617	CDD:227381	57/96 (59%)
		C2H2 Zn finger	526..546	CDD:275368	15/19 (79%)
		zf-H2C2_2	539..562	CDD:290200	15/22 (68%)
		C2H2 Zn finger	554..574	CDD:275368	14/19 (74%)
		zf-C2H2	554..574	CDD:278523	14/19 (74%)
		zf-H2C2_2	566..590	CDD:290200	14/23 (61%)
		C2H2 Zn finger	582..599	CDD:275368	12/16 (75%)
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	14/21 (67%)
		C2H2 Zn finger	121..141	CDD:275368	14/19 (74%)
		zf-C2H2	176..198	CDD:278523	15/21 (71%)
		C2H2 Zn finger	178..198	CDD:275368	15/19 (79%)
		zf-H2C2_2	191..214	CDD:290200	15/22 (68%)
		zf-C2H2	204..226	CDD:278523	14/21 (67%)
		C2H2 Zn finger	206..226	CDD:275368	14/19 (74%)
		zf-H2C2_2	218..242	CDD:290200	14/23 (61%)
		C2H2 Zn finger	234..250	CDD:275368	11/15 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449662
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D37106at7147
OrthoFinder	1	1.000	-	-		FOG0000984
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3156
SonicParanoid	1	1.000	-	-		X1445
	7	6.780