DRSC/TRiP Functional Genomics Resources

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Protein Alignment scrt and Zkscan3

DIOPT Version :9

Sequence 1:NP_001261390.1 Gene:scrt / 38469 FlyBaseID:FBgn0004880 Length:653 Species:Drosophila melanogaster
Sequence 2:NP_001012053.2 Gene:Zkscan3 / 306977 RGDID:1305753 Length:553 Species:Rattus norvegicus


Alignment Length:371 Identity:97/371 - (26%)
Similarity:142/371 - (38%) Gaps:73/371 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   246 YRPYSLDDKPAHGYRRRVPAEED---LHAAHAILDLSASTAFHPPTQPHQLQQQQQQQQQQHQHH 307
            |....||:.|.     :||.::|   |..:.|:|..||              |..:..|.:....
  Rat   128 YLDRQLDETPP-----QVPDDDDGQELLCSKAVLLTSA--------------QGSESSQMESMEP 173

  Fly   308 HSQQQHLAPQQHHYLPLQQQQQQQAHHTHLPTLEAHAHLRSTSSIAELAAAASVVNEQRPA-SNA 371
            ..:|:.|..     ||.:.:..|..|...    :.....|.||.:..|.....|.....|. :..
  Rat   174 LLKQESLGS-----LPSEVRVTQAGHCGE----DGVTATRLTSELQGLLKMEDVAPGLSPRWTEQ 229

  Fly   372 SSASSNHMPSSPSSNSSSSSSQVQNENSNTTNTNPDGDGCLQDGEHSGASGASAKTVAYTYEAFF 436
            .|:..|........||.|..|..:|..:...:..|..:...|..|         :||.:..|   
  Rat   230 DSSQMNLYKDEMQENSGSLVSLDENMQTKVRDLPPAEENTEQKPE---------QTVCFLGE--- 282

  Fly   437 VSDGRSKRKHVADPAAAASGVPTPDQQ------------KTKYTCSECGKQYATSSNLSRHKQTH 489
                        |.....:|....:|:            ..::.|.||||.:|.||.||:||:.|
  Rat   283 ------------DTVQIPTGTEASEQEGKLQTTQKNATGNRRFYCRECGKSFAQSSGLSKHKRIH 335

  Fly   490 RSLDSQSAKKCHTCGKAYVSMPALAMHLLTH--KLSHSCGVCGKLFSRPWLLQGHLRSHTGEKPY 552
            ..|   ...:|..||||::...||.:|...|  :..:.|..|||.||....|..|.|:|||||||
  Rat   336 TGL---KPYECEECGKAFIGSSALIIHQRVHTGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPY 397

  Fly   553 GCAHCGKAFADRSNLRAHMQTHSVDKNFECKRCHKTFALKSYLNKH 598
            .|..|||.|....:|..|.:.|:.:|.::|..|.|.|...|:|.:|
  Rat   398 ECDDCGKTFTQSCSLLEHHRIHTGEKPYQCNMCPKAFRRSSHLLRH 443

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scrtNP_001261390.1 zf-C2H2 467..489 CDD:278523 12/21 (57%)
C2H2 Zn finger 469..489 CDD:275370 12/19 (63%)
C2H2 Zn finger 500..520 CDD:275368 8/19 (42%)
COG5048 520..>617 CDD:227381 33/81 (41%)
C2H2 Zn finger 526..546 CDD:275368 9/19 (47%)
zf-H2C2_2 539..562 CDD:290200 14/22 (64%)
C2H2 Zn finger 554..574 CDD:275368 7/19 (37%)
zf-C2H2 554..574 CDD:278523 7/19 (37%)
zf-H2C2_2 566..590 CDD:290200 7/23 (30%)
C2H2 Zn finger 582..599 CDD:275368 7/17 (41%)
Zkscan3NP_001012053.2 SCAN 47..159 CDD:128708 10/35 (29%)
KRAB_A-box 213..271 CDD:413388 10/57 (18%)
zf-C2H2 313..335 CDD:395048 12/21 (57%)
C2H2 Zn finger 315..335 CDD:275368 12/19 (63%)
zf-H2C2_2 328..350 CDD:404364 10/24 (42%)
zf-C2H2 341..363 CDD:395048 8/21 (38%)
C2H2 Zn finger 343..363 CDD:275368 8/19 (42%)
COG5048 <367..514 CDD:227381 32/77 (42%)
C2H2 Zn finger 371..391 CDD:275368 9/19 (47%)
C2H2 Zn finger 399..419 CDD:275368 7/19 (37%)
C2H2 Zn finger 427..447 CDD:275368 7/17 (41%)
C2H2 Zn finger 481..501 CDD:275368
zf-C2H2 507..529 CDD:395048
C2H2 Zn finger 509..529 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 111 1.000 Inparanoid score I4772
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

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