DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scrt and Snai1

DIOPT Version :9

Sequence 1:	NP_001261390.1	Gene:	scrt / 38469	FlyBaseID:	FBgn0004880	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	NP_446257.1	Gene:	Snai1 / 116490	RGDID:	620758	Length:	264	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	108/321 - (33%)
Similarity:	131/321 - (40%)	Gaps:	116/321 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 HYLPLQ--------QQQQQQAH-------------HTHLPTL--------------EAHAHLRST 349
            :|..||        ||...|||             ...||||              .|...||.:
  Rat    18 NYSELQDACVEFTFQQPYDQAHLLAAIPPPEVLNPAASLPTLIWDSLLVPQVQPVAWATLPLRES 82

  Fly   350 SSIAELAAAASVVNEQRPASNASSASSNHMPSSPSSNSSSSSSQVQNENSNTTNTNPDGDGCLQD 414
            ...|||.:          .|:..|..|:..||.||...||.||
  Rat    83 PRAAELTS----------LSDEDSGKSSQPPSPPSPAPSSFSS---------------------- 115

  Fly   415 GEHSGASGASAKTVAYTYEAFFVSDGRSKRKHVADPAAAASGVPTPDQQKTKYTCSECGKQYATS 479
               :.||...|       |||....|                            ..:..||.|
  Rat   116 ---TSASSLEA-------EAFIAFPG----------------------------LGQLPKQLA-- 140

  Fly   480 SNLSRHKQTHRSLDSQSAK--KCHTCGKAYVSMPALAMHLLTHKLSHSCGVCGKLFSRPWLLQGH 542
             .||..|      |.||.|  .|..|.|.|:|:.||.||:.:|.|...|..|||.||||||||||
  Rat   141 -RLSVAK------DPQSRKAFNCKYCNKEYLSLGALKMHIRSHTLPCVCTTCGKAFSRPWLLQGH 198

  Fly   543 LRSHTGEKPYGCAHCGKAFADRSNLRAHMQTHSVDKNFECKRCHKTFALKSYLNKHLESAC 603
            :|:||||||:.|:||.:|||||||||||:||||..|.::|:.|.:||:..|.|:||.||.|
  Rat   199 VRTHTGEKPFSCSHCNRAFADRSNLRAHLQTHSDVKRYQCQACARTFSRMSLLHKHQESGC 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scrt	NP_001261390.1	zf-C2H2	467..489	CDD:278523	6/21 (29%)
		C2H2 Zn finger	469..489	CDD:275370	6/19 (32%)
		C2H2 Zn finger	500..520	CDD:275368	9/19 (47%)
		COG5048	520..>617	CDD:227381	53/84 (63%)
		C2H2 Zn finger	526..546	CDD:275368	15/19 (79%)
		zf-H2C2_2	539..562	CDD:290200	15/22 (68%)
		C2H2 Zn finger	554..574	CDD:275368	15/19 (79%)
		zf-C2H2	554..574	CDD:278523	15/19 (79%)
		zf-H2C2_2	566..590	CDD:290200	13/23 (57%)
		C2H2 Zn finger	582..599	CDD:275368	7/16 (44%)
Snai1	NP_446257.1	C2H2 Zn finger	156..176	CDD:275368	9/19 (47%)
		COG5048	<177..>253	CDD:227381	47/75 (63%)
		zf-C2H2	180..202	CDD:278523	15/21 (71%)
		C2H2 Zn finger	182..202	CDD:275368	15/19 (79%)
		zf-H2C2_2	195..218	CDD:290200	15/22 (68%)
		zf-C2H2	208..230	CDD:278523	15/21 (71%)
		C2H2 Zn finger	210..230	CDD:275368	15/19 (79%)
		C2H2 Zn finger	238..255	CDD:275368	7/16 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810