DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scrt and scrt2

DIOPT Version :9

Sequence 1:	NP_001261390.1	Gene:	scrt / 38469	FlyBaseID:	FBgn0004880	Length:	653	Species:	Drosophila melanogaster
Sequence 2:	XP_031760336.1	Gene:	scrt2 / 100486069	XenbaseID:	XB-GENE-5995512	Length:	278	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	142/273 - (52%)
Similarity:	172/273 - (63%)	Gaps:	31/273 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   333 HHTHLPTLEAHAHLRSTSSIAELAAAASVVNEQRPASNASSASSNHMPSSPSSNSSSSSSQVQNE 397
            |.|...|     ||.....::|..|.:....:...|....|..:.: .:..|...::.|....:.
Frog    26 HRTDFST-----HLSDKGYLSEYIAPSVYDGDSDGAIKVPSPDALY-TTVHSEYGAADSEPPDSP 84

  Fly   398 NSNTTNTNPDGDGCLQDGEHSGASGASAKTVAYTYEAFFVSDGRSKRKHVADPAAAASGVPTPDQ 462
            .|..|....:||..:.:|              |:.:|||::||||:||           |.:..:
Frog    85 RSEITGGYINGDAAVSEG--------------YSVDAFFITDGRSRRK-----------VLSGGR 124

  Fly   463 QKTKYTCSECGKQYATSSNLSRHKQTHRSLDSQSAKKCHTCGKAYVSMPALAMHLLTHKLSHSCG 527
            ...:::||||||.|||||||||||||||||||:.||||.||||.||||||:|||||||.|.|.|.
Frog   125 SIQRHSCSECGKSYATSSNLSRHKQTHRSLDSKLAKKCPTCGKVYVSMPAMAMHLLTHDLKHKCE 189

  Fly   528 VCGKLFSRPWLLQGHLRSHTGEKPYGCAHCGKAFADRSNLRAHMQTHSVDKNFECKRCHKTFALK 592
            .|||.||||||||||:||||||||:|||||||||||||||||||||||..|:::||||.||||||
Frog   190 TCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYKCKRCSKTFALK 254

  Fly   593 SYLNKHLESACLK 605
            ||||||.||||.|
Frog   255 SYLNKHYESACFK 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scrt	NP_001261390.1	zf-C2H2	467..489	CDD:278523	18/21 (86%)
		C2H2 Zn finger	469..489	CDD:275370	18/19 (95%)
		C2H2 Zn finger	500..520	CDD:275368	16/19 (84%)
		COG5048	520..>617	CDD:227381	70/86 (81%)
		C2H2 Zn finger	526..546	CDD:275368	15/19 (79%)
		zf-H2C2_2	539..562	CDD:290200	20/22 (91%)
		C2H2 Zn finger	554..574	CDD:275368	19/19 (100%)
		zf-C2H2	554..574	CDD:278523	19/19 (100%)
		zf-H2C2_2	566..590	CDD:290200	17/23 (74%)
		C2H2 Zn finger	582..599	CDD:275368	15/16 (94%)
scrt2	XP_031760336.1	C2H2 Zn finger	131..151	CDD:275368	18/19 (95%)
		C2H2 Zn finger	162..179	CDD:275371	13/16 (81%)
		COG5048	186..>262	CDD:227381	63/75 (84%)
		C2H2 Zn finger	188..208	CDD:275368	15/19 (79%)
		C2H2 Zn finger	216..236	CDD:275368	19/19 (100%)
		C2H2 Zn finger	244..260	CDD:275368	14/15 (93%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11387
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1332418at2759
OrthoFinder	1	1.000	-	-		FOG0000984
OrthoInspector	1	1.000	-	-		mtm9535
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1445
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010